Mitsugu Akagawa
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Explore the profile of Mitsugu Akagawa including associated specialties, affiliations and a list of published articles.
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51
Citations
833
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Recent Articles
1.
Kato Y, Suzuki S, Higashiyama A, Kaneko I, Akagawa M, Nishikawa M, et al.
J Agric Food Chem
. 2025 Feb;
73(7):4116-4125.
PMID: 39907399
We herein examined the inhibitory effects of tea catechins on the SARS-CoV-2 main protease (M). Among the catechins analyzed, epigallocatechin 3-(3″--methyl)gallate, epigallocatechin gallate (EGCG), gallocatechin, gallocatechin gallate, and epigallocatechin inhibited...
2.
Kamikubo R, Yoshida H, Fushimi T, Kamei Y, Akagawa M
Biosci Biotechnol Biochem
. 2024 Sep;
88(12):1465-1471.
PMID: 39271459
β-Caryophyllene (BCP), a dietary phytocannabinoid, significantly suppresses palmitate-induced lipid accumulation in human HepG2 hepatocytes via activation of AMP-activated protein kinase (AMPK) signaling. The objective of the preset research was to...
3.
Ikemoto K, Ishak N, Akagawa M
J Med Invest
. 2024 May;
71(1.2):23-28.
PMID: 38735721
Pyrroloquinoline quinone disodium salt (PQQ) is a red trihydrate crystal that was approved as a new food ingredient by FDA in 2008. Now, it is approved as a food in...
4.
Kitao M, Yamaguchi A, Tomioka T, Kai K, Kamei Y, Sugimoto K, et al.
Free Radic Res
. 2023 Oct;
57(6-12):430-443.
PMID: 37897411
Age-related macular degeneration (AMD) is one of an increasing number of diseases that causes irreversible impairment and loss of vision in the elderly. AMD occurs by oxidative stress-mediated apoptosis of...
5.
Yamaguchi K, Itakura M, Kitazawa R, Lim S, Nagata K, Shibata T, et al.
J Biol Chem
. 2021 Aug;
297(3):101035.
PMID: 34339739
Polyphenols, especially catechol-type polyphenols, exhibit lysyl oxidase-like activity and mediate oxidative deamination of lysine residues in proteins. Previous studies have shown that polyphenol-mediated oxidative deamination of lysine residues can be...
6.
Oshimo M, Nakashima F, Kai K, Matsui H, Shibata T, Akagawa M
Free Radic Res
. 2021 Jun;
55(6):731-743.
PMID: 34074194
Sulfites are commonly used as a preservative and antioxidant additives in the food industry. Sulfites are absorbed by the gastrointestinal tract and distributed essentially to all body tissues. Although sulfites...
7.
Akagawa M
Free Radic Res
. 2020 Nov;
55(4):307-320.
PMID: 33183115
Proteins are oxidatively modified by a large number of reactive species including reactive oxygen species, lipid peroxidation-derived aldehydes, and reducing sugars. Among divergent oxidative modifications, the introduction of carbonyl groups...
8.
Kusu H, Yoshida H, Kudo M, Okuyama M, Harada N, Tsuji-Naito K, et al.
Mol Nutr Food Res
. 2019 Aug;
63(22):e1801377.
PMID: 31454158
Scope: Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common chronic liver disease worldwide, defined by hepatic over-accumulation of lipids without significant ethanol consumption. Pharmacological or bioactive food...
9.
Yoshida H, Ishii M, Akagawa M
Arch Biochem Biophys
. 2019 Jul;
672:108057.
PMID: 31356781
Short-chain fatty acids (SCFAs) such as acetate, propionate, and butyrate are generated by gut microbial fermentation of dietary fiber. SCFAs may exert multiple beneficial effects on human lipid and glucose...
10.
Yagi M, Nakatsuji Y, Maeda A, Ota H, Kamikubo R, Miyoshi N, et al.
PLoS One
. 2018 Nov;
13(11):e0206748.
PMID: 30383868
Obesity, a principal risk factor for the development of diabetes mellitus, heart disease, and hypertension, is a growing and serious health problem all over the world. Leptin is a weight-reducing...