Mitro Miihkinen
Overview
Explore the profile of Mitro Miihkinen including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
156
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Recent Articles
1.
Metsala O, Wahlstrom G, Goel N, Miihkinen M, Taimen P, Schleutker J
J Pathol
. 2025 Feb;
265(4):518-531.
PMID: 39978863
Prostate cancer (PrCa) is highly prevalent in the Western world. Currently, however, there are many unmet needs in PrCa care, for example in distinguishing between clinically significant and indolent cases...
2.
Ianevski A, Kushnir A, Nader K, Miihkinen M, Xhaard H, Aittokallio T, et al.
Brief Bioinform
. 2024 Jul;
25(4).
PMID: 38980370
RepurposeDrugs (https://repurposedrugs.org/) is a comprehensive web-portal that combines a unique drug indication database with a machine learning (ML) predictor to discover new drug-indication associations for approved as well as investigational...
3.
Nader K, Tasci M, Ianevski A, Erickson A, Verschuren E, Aittokallio T, et al.
Bioinformatics
. 2024 Jun;
40(7).
PMID: 38936341
Summary: The limited resolution of spatial transcriptomics (ST) assays in the past has led to the development of cell type annotation methods that separate the convolved signal based on available...
4.
Khan M, Salomaa S, Jacquemet G, Butt U, Miihkinen M, Deguchi T, et al.
J Cell Sci
. 2023 Oct;
136(19).
PMID: 37823537
No abstract available.
5.
Popovic A, Miihkinen M, Ghimire S, Saup R, Gronloh M, Ball N, et al.
J Cell Sci
. 2023 Mar;
136(5).
PMID: 36861887
Myosin-X (MYO10), a molecular motor localizing to filopodia, is thought to transport various cargo to filopodia tips, modulating filopodia function. However, only a few MYO10 cargoes have been described. Here,...
6.
Salomaa S, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, et al.
Curr Biol
. 2021 Oct;
31(22):4956-4970.e9.
PMID: 34610274
Actin-rich cellular protrusions direct versatile biological processes from cancer cell invasion to dendritic spine development. The stability, morphology, and specific biological functions of these protrusions are regulated by crosstalk between...
7.
Miihkinen M, Gronloh M, Popovic A, Vihinen H, Jokitalo E, Goult B, et al.
Cell Rep
. 2021 Sep;
36(11):109716.
PMID: 34525374
Filopodia assemble unique integrin-adhesion complexes to sense the extracellular matrix. However, the mechanisms of integrin regulation in filopodia are poorly defined. Here, we report that active integrins accumulate at the...
8.
Stubb A, Laine R, Miihkinen M, Hamidi H, Guzman C, Henriques R, et al.
Nano Lett
. 2020 Mar;
20(4):2230-2245.
PMID: 32142297
Cellular mechanics play a crucial role in tissue homeostasis and are often misregulated in disease. Traction force microscopy is one of the key methods that has enabled researchers to study...
9.
Stubb A, Guzman C, Narva E, Aaron J, Chew T, Saari M, et al.
Nat Commun
. 2019 Oct;
10(1):4756.
PMID: 31628312
While it is clear that key transcriptional programmes are important for maintaining pluripotency, the requirement for cell adhesion to the extracellular matrix remains poorly defined. Human pluripotent stem cells (hPSCs)...
10.
Jacquemet G, Stubb A, Saup R, Miihkinen M, Kremneva E, Hamidi H, et al.
Curr Biol
. 2019 Jan;
29(2):202-216.e7.
PMID: 30639111
Filopodia are adhesive cellular protrusions specialized in the detection of extracellular matrix (ECM)-derived cues. Although ECM engagement at focal adhesions is known to trigger the recruitment of hundreds of proteins...