Mitchell Bacho
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Explore the profile of Mitchell Bacho including associated specialties, affiliations and a list of published articles.
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6
Citations
8
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Recent Articles
1.
Zuniga-Hernandez J, Quinones San Martin M, Figueroa B, Novoa U, Monsalve F, Bacho M, et al.
Pharmaceuticals (Basel)
. 2024 Jun;
17(6).
PMID: 38931413
() is a shrub of the Andean Altiplano of Bolivia, Chile and Peru, consumed by local communities as a traditional medicine for several maladies such as diabetes, hepatic and inflammatory...
2.
Andrade V, Wong-Guerra M, Cortes N, Pastor G, Gonzalez A, Calfio C, et al.
Pharmaceuticals (Basel)
. 2023 Jul;
16(7).
PMID: 37513872
Alzheimer's disease (AD) is a multifactorial neurodegenerative disorder without a cure, despite the enormous number of investigations and therapeutic approaches. AD is a consequence of microglial responses to "damage signals",...
3.
Bacho M, Artigas V, Araya-Contreras T, Bittner M, Escobar C, Fuentealba M, et al.
Nat Prod Res
. 2021 Jun;
37(1):16-23.
PMID: 34187247
In this study, we report a facile transformation starting from 5α-hydroxyergosta-7,22-dien-3,6-dione to afford two novel compounds: 6-methoxyergosta-4,6,8(14),22-tetraen-3-one and 6-ethoxyergosta-4,6,8(14),22-tetraen-3-one ( using alcoholic acid catalysis. Their structures were elucidated using NMR...
4.
Bacho M, Coelho-Cerqueira E, Follmer C, Nabavi S, Rastrelli L, Uriarte E, et al.
Curr Top Med Chem
. 2016 Aug;
17(4):489-497.
PMID: 27558674
Background: A series of perimidinone derivatives (7H-benzo[e]perimidin-7-one) were synthesized and assessed by means of in vitro assays as human MAO inhibitors. These compounds inhibited reversibly the enzymes with inhibitory constants...
5.
Donoso V, Bacho M, Nuinez S, Rovirosa J, San-Martin A, Leiva S
Nat Prod Commun
. 2016 Jan;
10(11):1915-6.
PMID: 26749825
The present study was aimed at evaluating the antibacterial activity of mulinane and azorellane diterpenes isolated from the Andean plants Azorella compacta and A. trifoliolata and semisynthetic derivatives against reference...
6.
San-Martin A, Donoso V, Leiva S, Bacho M, Nunez S, Gutierrez M, et al.
Curr Top Med Chem
. 2015 Apr;
15(17):1743-9.
PMID: 25915607
Phytochemical investigation of Azorella madreporica led to the isolation of four known compounds and an unknown chalcone. The structure of the new compound was identified by spectroscopy, including two-dimensional NMR...