Miriam Melis
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Explore the profile of Miriam Melis including associated specialties, affiliations and a list of published articles.
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76
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2504
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Recent Articles
11.
Sagheddu C, Melis M, Muntoni A, Pistis M
Pharmaceuticals (Basel)
. 2021 Oct;
14(10).
PMID: 34681249
Common pathophysiological mechanisms have emerged for different neurological and neuropsychiatric conditions. In particular, mechanisms of oxidative stress, immuno-inflammation, and altered metabolic pathways converge and cause neuronal and non-neuronal maladaptative phenomena,...
12.
Ciccocioppo R, de Guglielmo G, Li H, Melis M, Caffino L, Shen Q, et al.
J Neurosci
. 2021 Jun;
41(28):6128-6143.
PMID: 34083258
Approximately 5 million people die from diseases related to nicotine addiction and tobacco use each year. The nicotine-induced increase of corticomesolimbic dopaminergic (DAergic) transmission and hypodopaminergic conditions occurring during abstinence...
13.
Porcu A, Mostallino R, Serra V, Melis M, Sogos V, Beggiato S, et al.
Neuropharmacology
. 2021 Apr;
189:108537.
PMID: 33798546
Allosteric modulators of G protein coupled receptors (GPCRs), including GABARs (GABARs), are promising therapeutic candidates. While several positive allosteric modulators (PAM) of GABARs have been characterized, only recently the first...
14.
Traccis F, Serra V, Sagheddu C, Congiu M, Saba P, Giua G, et al.
Int J Mol Sci
. 2021 Feb;
22(4).
PMID: 33562259
Cannabis use among pregnant women is increasing worldwide along with permissive sociocultural attitudes toward it. Prenatal cannabis exposure (PCE), however, is associated with adverse outcome among offspring, ranging from reduced...
15.
Murru E, Carta G, Manca C, Sogos V, Pistis M, Melis M, et al.
Front Pharmacol
. 2021 Jan;
11:587140.
PMID: 33505308
Fatty acids play a crucial role in the brain as specific receptor ligands and as precursors of bioactive metabolites. Conjugated linoleic acid (CLA), a group of positional and geometric isomers...
16.
Lujan M, Cheer J, Melis M
Curr Opin Pharmacol
. 2020 Oct;
56:29-38.
PMID: 33068883
Prolonged exposure to drugs of abuse leads to severe alterations in mesocorticolimbic dopamine circuitry deeply implicated in substance use disorders. Despite considerable efforts, few medications to reduce relapse rates are...
17.
Sagheddu C, Traccis F, Serra V, Congiu M, Frau R, Cheer J, et al.
Prog Neuropsychopharmacol Biol Psychiatry
. 2020 Oct;
105:110128.
PMID: 33031862
Cannabis is the illicit drug most widely used by pregnant women worldwide. Its growing acceptance and legalization have markedly increased the risks of child psychopathology, including psychotic-like experiences, which lowers...
18.
Medrano M, Hurel I, Mesguich E, Redon B, Stevens C, Georges F, et al.
Addict Biol
. 2020 Oct;
26(3):e12967.
PMID: 33021007
Physical exercise, which can be addictogenic on its own, is considered a therapeutic alternative for drug craving. Exercise might thus share with drugs the ability to strengthen excitatory synapses onto...
19.
Traccis F, Frau R, Melis M
Front Behav Neurosci
. 2020 Jun;
14:72.
PMID: 32581736
Despite great efforts to warn pregnant women that drugs of abuse impact development of the embryo and the fetus, the use of legal and illegal drugs by childbearing women is...
20.
Hurd Y, Manzoni O, Pletnikov M, Lee F, Bhattacharyya S, Melis M
J Neurosci
. 2019 Oct;
39(42):8250-8258.
PMID: 31619494
The recent shift in sociopolitical debates and growing liberalization of cannabis use across the globe has raised concern regarding its impact on vulnerable populations, such as pregnant women and adolescents....