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Miriam Geissler

Explore the profile of Miriam Geissler including associated specialties, affiliations and a list of published articles. Areas
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Articles 4
Citations 54
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Recent Articles
1.
Hiller M, Geissler M, Janssen G, van Veelen P, Aartsma-Rus A, Spitali P
Genomics Proteomics Bioinformatics . 2020 Dec; 18(4):384-396. PMID: 33338663
Muscle formation is a coordinated process driven by extensive gene expression changes where single cells fuse together to form multinucleated muscle fibers. Newly synthesized mRNAs are then regulated by RNA...
2.
Geissler A, Geissler M, Kottmann D, Lutz L, Fichter C, Fritsch R, et al.
Oncotarget . 2017 Feb; 8(10):17164-17190. PMID: 28199979
EGFR-targeted therapy is a key treatment approach in patients with RAS wildtype metastatic colorectal cancers (CRC). Still, also RAS wildtype CRC may be resistant to EGFR-targeted therapy, with few predictive...
3.
Braeuning A, Gavrilov A, Geissler M, Wenz C, Colnot S, Templin M, et al.
Arch Toxicol . 2016 Feb; 90(6):1481-94. PMID: 26838046
Activation of Wnt/β-catenin signaling is important for human and rodent hepatocarcinogenesis. In mice, the tumor promoter phenobarbital (PB) selects for hepatocellular tumors with activating β-catenin mutations via constitutive androstane receptor...
4.
Luisier R, Lempiainen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, et al.
Toxicol Sci . 2014 Apr; 139(2):501-11. PMID: 24690595
The constitutive androstane receptor (CAR) and the pregnane X receptor (PXR) are closely related nuclear receptors involved in drug metabolism and play important roles in the mechanism of phenobarbital (PB)-induced...