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Christiane D Fichter

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Recent Articles
1.
Geissler A, Geissler M, Kottmann D, Lutz L, Fichter C, Fritsch R, et al.
Oncotarget . 2017 Feb; 8(10):17164-17190. PMID: 28199979
EGFR-targeted therapy is a key treatment approach in patients with RAS wildtype metastatic colorectal cancers (CRC). Still, also RAS wildtype CRC may be resistant to EGFR-targeted therapy, with few predictive...
2.
Sijare F, Geissler A, Fichter C, Hergeth S, Bogatyreva L, Hauschke D, et al.
Virchows Arch . 2015 Feb; 466(5):503-15. PMID: 25680570
Experimental model systems identified phosphorylation of linker histone variant H1.4 at Ser 27 (H1.4S27p) as a novel mitotic mark set by Aurora B kinase. Here, we examined expression of Aurora...
3.
Fichter C, Gudernatsch V, Przypadlo C, Follo M, Schmidt G, Werner M, et al.
J Mol Med (Berl) . 2014 Aug; 92(11):1209-23. PMID: 25091467
Unlabelled: ErbB family receptor tyrosine kinases (ErbBs) play a role in cell adhesion and migration and are frequently overexpressed in esophageal squamous cell carcinomas (ESCCs) or esophageal adenocarcinomas (EACs). Targeting...
4.
Herz C, Schlurmann F, Batarello D, Fichter C, Schopflin A, Munch C, et al.
Mol Carcinog . 2011 Jul; 51(9):696-710. PMID: 21739483
Aurora A "over-"expression may induce supernumerary centrosomes, respective multipolar mitoses, and aneuploidy. Here, we examined Aurora A positive multipolar mitoses in aneuploid, microsatellite-stable (MSS, "CIN-type") versus near-diploid, microsatellite-instable (MSI, "MIN-type")...
5.
Fichter C, Herz C, Munch C, Opitz O, Werner M, Lassmann S
BMC Cell Biol . 2011 Apr; 12:13. PMID: 21470402
Background: Aurora kinases and loss of p53 function are implicated in the carcinogenesis of aneuploid esophageal cancers. Their association with occurrence of multipolar mitoses in the two main histotypes of...
6.
Wagner K, Perschil I, Fichter C, van der Laan M
Mol Biol Cell . 2010 Mar; 21(9):1494-504. PMID: 20219971
F(1)F(o)-ATP synthase is a key enzyme of oxidative phosphorylation that is localized in the inner membrane of mitochondria. It uses the energy stored in the proton gradient across the inner...