Miriam B F Werneck
Overview
Explore the profile of Miriam B F Werneck including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
893
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0
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Recent Articles
1.
Melo G, Xu T, Caloba C, Schutte A, Passos T, Neto M, et al.
J Immunol
. 2023 Jul;
211(5):721-726.
PMID: 37486206
CTL differentiation is controlled by the crosstalk of various transcription factors and epigenetic modulators. Uncovering this process is fundamental to improving immunotherapy and designing novel therapeutic approaches. In this study,...
2.
Neitzke-Montinelli V, Caloba C, Melo G, Frade B, Caramez E, Mazzoccoli L, et al.
Front Immunol
. 2022 Jun;
13:840203.
PMID: 35677061
Long-term immunological protection relies on the differentiation and maintenance of memory lymphocytes. Since the knowledge of memory generation has been centered on models of infection, there are obstacles to deep...
3.
Fazolini N, Cruz A, Werneck M, Viola J, Maya-Monteiro C, Bozza P
Cell Cycle
. 2015 May;
14(16):2667-76.
PMID: 26017929
Accumulating evidence suggests that obesity and enhanced inflammatory reactions are predisposing conditions for developing colon cancer. Obesity is associated with high levels of circulating leptin. Leptin is an adipocytokine that...
4.
Werneck M, Hottz E, Bozza P, Viola J
Cell Cycle
. 2012 Sep;
11(21):3997-4008.
PMID: 22992618
Chronic inflammation is a risk factor for the development of colon cancer, providing genotoxic insults, growth and pro-angiogenic factors that can promote tumorigenesis and tumor growth. Immunomodulatory agents can interfere...
5.
Wang X, Werneck M, Wilson B, Kim H, Kluk M, Thom C, et al.
J Clin Invest
. 2011 Sep;
121(10):3834-45.
PMID: 21926465
A fundamental goal in cancer research is the identification of the cell types and signaling pathways capable of initiating and sustaining tumor growth, as this has the potential to reveal...
6.
Werneck M, Vieira-de-Abreu A, Chammas R, Viola J
Cancer Immunol Immunother
. 2011 Jan;
60(4):537-46.
PMID: 21225259
Members of the nuclear factor of activated T cell (NFAT) family of transcription factors were originally described in T lymphocytes but later shown to be expressed in several immune and...
7.
Lugo-Villarino G, Balla K, Stachura D, Banuelos K, Werneck M, Traver D
Proc Natl Acad Sci U S A
. 2010 Aug;
107(36):15850-5.
PMID: 20733076
In mammals, dendritic cells (DCs) form the key link between the innate and adaptive immune systems. DCs act as immune sentries in various tissues and, upon encountering pathogen, engulf and...
8.
Lu L, Kim H, Werneck M, Cantor H
Proc Natl Acad Sci U S A
. 2008 Dec;
105(49):19420-5.
PMID: 19047627
Regulation of autoreactive CD4 T cells is essential to maintain self-tolerance and prevent autoimmune disease. Although CD8 T regulatory (Treg) cells that recognize self-peptides restricted by Qa-1 (HLA-E in humans)...
9.
Robbs B, Cruz A, Werneck M, Mognol G, Viola J
Mol Cell Biol
. 2008 Sep;
28(23):7168-81.
PMID: 18809576
Nuclear factor of activated T cells (NFAT) was first described as an activation and differentiation transcription factor in lymphocytes. Several in vitro studies suggest that NFAT family members are redundant...
10.
Werneck M, Lugo-Villarino G, Hwang E, Cantor H, Glimcher L
J Immunol
. 2008 Jun;
180(12):8004-10.
PMID: 18523263
Antitumor responses depend on type 1 immunity, which is severely impaired in mice deficient for the T-box expressed in T cells (T-bet) transcription factor. Both T-bet-deficient (T-bet(-/-)) NK and CTL...