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Miranda D Grounds

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Articles 118
Citations 2635
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Recent Articles
1.
Lloyd E, Hepburn M, Li J, Mowla A, Jeong J, Hwang Y, et al.
J Mech Behav Biomed Mater . 2024 Sep; 160:106751. PMID: 39326249
Skeletal muscle tissue function is governed by the mechanical properties and organization of its components, including myofibers, extracellular matrix, and adipose tissue, which can be modified by the onset and...
2.
Sayer A, Cooper R, Arai H, Cawthon P, Essomba M, Fielding R, et al.
Nat Rev Dis Primers . 2024 Sep; 10(1):68. PMID: 39300120
Sarcopenia is the accelerated loss of skeletal muscle mass and function commonly, but not exclusively, associated with advancing age. It is observed across many species including humans in whom it...
3.
Lloyd E, Crew R, Haynes V, White R, Mark P, Jackaman C, et al.
Skelet Muscle . 2024 Aug; 14(1):19. PMID: 39123261
Background: Dysferlinopathies are a clinically heterogeneous group of muscular dystrophies caused by gene mutations resulting in deficiency of the membrane-associated protein dysferlin. They manifest post-growth and are characterised by muscle...
4.
Terrill J, Bautista A, Tsioutsias I, Grounds M, Arthur P
Antioxidants (Basel) . 2024 Jun; 13(6). PMID: 38929159
Redox modifications to the plasma protein albumin have the potential to be used as biomarkers of disease progression and treatment efficacy in pathologies associated with inflammation and oxidative stress. One...
5.
Granic A, Suetterlin K, Shavlakadze T, Grounds M, Sayer A
Clin Sci (Lond) . 2023 Nov; 137(22):1721-1751. PMID: 37986616
Ageing is a complex biological process associated with increased morbidity and mortality. Nine classic, interdependent hallmarks of ageing have been proposed involving genetic and biochemical pathways that collectively influence ageing...
6.
Grounds M, Lloyd E
J Neuromuscul Dis . 2023 Nov; 10(6):1013-1030. PMID: 37927274
This commentary provides an independent consideration of data related to the drug vamorolone (VBP15) as an alternative steroid proposed for treatment of Duchenne muscular dystrophy (DMD). Glucocorticoids such as prednisone...
7.
Lloyd E, Pinniger G, Murphy R, Grounds M
Acta Physiol (Oxf) . 2023 Jun; 238(4):e14012. PMID: 37306196
Many neuromuscular disorders can have a differential impact on a specific myofibre type, forming the central premise of this review. The many different skeletal muscles in mammals contain a spectrum...
8.
Lloyd E, Xu H, Murphy R, Grounds M, Pinniger G
PLoS One . 2023 May; 18(5):e0286286. PMID: 37216378
[This corrects the article DOI: 10.1371/journal.pone.0214908.].
9.
Terrill J, Huchet C, Le Guiner C, Lafoux A, Caudal D, Tulangekar A, et al.
Metabolites . 2023 Feb; 13(2). PMID: 36837851
Inflammation and oxidative stress are strongly implicated in the pathology of Duchenne muscular dystrophy (DMD), and the sulphur-containing amino acid taurine ameliorates both and decreases dystropathology in the mouse model...
10.
Lloyd E, Hepburn M, Li J, Mowla A, Hwang Y, Choi Y, et al.
Biomed Opt Express . 2023 Feb; 13(11):5879-5899. PMID: 36733728
Skeletal muscle function is governed by both the mechanical and structural properties of its constituent tissues, which are both modified by disease. Characterizing the mechanical properties of skeletal muscle tissue...