Mirabelle Dagarag
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Explore the profile of Mirabelle Dagarag including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
338
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Recent Articles
1.
Lewis M, Dagarag M, Khan B, Ali A, Yang O
J Virol
. 2012 May;
86(13):7459-63.
PMID: 22553321
Viral mutational escape from CD8(+) cytotoxic T lymphocytes (CTLs) is typically considered to be a dichotomous process and uncommon during chronic HIV-1 infection. Ex vivo passaging of HIV-1 from persons...
2.
Bennett M, Ng H, Dagarag M, Ali A, Yang O
J Virol
. 2007 Mar;
81(10):4973-80.
PMID: 17329324
Cytotoxic T lymphocytes (CTLs) are crucial for immune control of viral infections. "Functional avidity," defined by the sensitizing dose of exogenously added epitope yielding half-maximal CTL triggering against uninfected target...
3.
Effros R, Dagarag M, Spaulding C, Man J
Immunol Rev
. 2005 May;
205:147-57.
PMID: 15882351
The strict limit in proliferative potential of normal human somatic cells - a process known as replicative senescence - is highly relevant to the immune system, because clonal expansion is...
4.
Sabado R, Kilpatrick S, Ali A, Dagarag M, Ng H, Cao H, et al.
J Immunol Methods
. 2005 Feb;
296(1-2):1-10.
PMID: 15680145
The variability of HIV-1 sequences within and between persons in vivo complicates immunologic screening with a fixed sequence, and using peptides based on consensus sequences therefore has become a common...
5.
Yang O, Lin H, Dagarag M, Ng H, Effros R, Uittenbogaart C
Virology
. 2005 Jan;
332(1):16-9.
PMID: 15661136
Cytotoxic T lymphocyte (CTL) senescence may be an important mechanism of immune failure in HIV-1 infection. We find that senescence of HIV-1-specific CTL clones causes loss of killing activity, preventable...
6.
Dagarag M, Evazyan T, Rao N, Effros R
J Immunol
. 2004 Nov;
173(10):6303-11.
PMID: 15528369
A large proportion of the CD8(+) T cell pool in persons chronically infected with HIV consists of cells that show features of replicative senescence, an end stage characterized by irreversible...
7.
Effros R, Dagarag M, Valenzuela H
Exp Gerontol
. 2003 Dec;
38(11-12):1243-9.
PMID: 14698803
Immune cells are eminently suitable model systems in which to address the possible role of replicative senescence during in vivo aging. Since there are more than 10(8) unique antigen specificities...
8.
Dagarag M, Ng H, Lubong R, Effros R, Yang O
J Virol
. 2003 Feb;
77(5):3077-83.
PMID: 12584333
Telomere length is abnormally short in the CD8(+) T-cell compartment of human immunodeficiency virus type 1 (HIV-1)-infected persons, likely because of chronic cell turnover. Although clonal exhaustion of CD8(+) cytotoxic...