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Mira C P Liu

Explore the profile of Mira C P Liu including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 306
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Recent Articles
1.
Wong C, Chen A, Liu M, Parker B, Moller A
Microvasc Res . 2015 Aug; 102:38-45. PMID: 26275748
Angiogenesis is triggered in response to hypoxia under many circumstances, from healthy cells and tissues during embryogenesis to pathological conditions like the formation of new blood vessels to supply tumours...
2.
Chen A, Wong C, Liu M, House C, Sceneay J, Bowtell D, et al.
Oncotarget . 2014 Dec; 6(2):862-73. PMID: 25528765
Elucidating the mechanisms that underlie metastasis is of paramount importance to understanding tumor progression and to the development of novel therapeutics. Epithelial to Mesenchymal Transition (EMT) plays a vital role...
3.
Sceneay J, Liu M, Chen A, Wong C, Bowtell D, Moller A
PLoS One . 2013 Jul; 8(6):e66388. PMID: 23840457
Intratumoral hypoxia is a poor prognostic factor associated with reduced disease-free survival in many cancer types, including breast cancer. Hypoxia encourages tumor cell proliferation, stimulates angiogenesis and lymphangiogenesis, and promotes...
4.
Musyoka J, Liu M, Pouniotis D, Wong C, Bowtell D, Little P, et al.
Wound Repair Regen . 2013 May; 21(3):437-47. PMID: 23627548
Hypoxia is associated with the dermal wound healing process and hypoxia signaling is presumed to be crucial for normal wound repair. The Siah2 ubiquitin ligase controls the abundance of hypoxia-inducible...
5.
Stagg J, Beavis P, Divisekera U, Liu M, Moller A, Darcy P, et al.
Cancer Res . 2012 Mar; 72(9):2190-6. PMID: 22396496
CD73 is a cell surface 5'-nucleotidase that converts AMP to adenosine, an immune suppressive molecule. CD73 may promote immune escape in cancer by contributing to the degradation of extracellular ATP...
6.
Wong C, Sceneay J, House C, Halse H, Liu M, George J, et al.
Cancer Res . 2012 Feb; 72(7):1694-704. PMID: 22354750
Tumor hypoxia is associated with resistance to antiangiogenic therapy and poor prognosis. The Siah E3 ubiquitin ligases regulate the hypoxic response pathway by modulating the turnover of the master proangiogenic...
7.
Chan P, Moller A, Liu M, Sceneay J, Wong C, Waddell N, et al.
Breast Cancer Res . 2011 Feb; 13(1):R19. PMID: 21306611
Introduction: The seven in absentia homolog 2 (SIAH2) protein plays a significant role in the hypoxic response by regulating the abundance of hypoxia-inducible factor-α; however, its role in breast carcinoma...
8.
Haylock D, Williams B, Johnston H, Liu M, Rutherford K, Whitty G, et al.
Stem Cells . 2007 Apr; 25(4):1062-9. PMID: 17420230
It is now evident that hemopoietic stem cells (HSC) are located in close proximity to bone lining cells within the endosteum. Accordingly, it is unlikely that the traditional method for...
9.
Liu M, Choong D, Hooi C, Williams L, Campbell I
Cancer Lett . 2006 Apr; 247(1):91-7. PMID: 16644110
Chromosome 22q shows a high frequency of loss of heterozygosity (LOH) in ovarian cancers suggesting the existence of one or more important tumor suppressor genes (TSGs). The tissue inhibitor of...
10.
Montgomery K, Liu M, Eccles D, Campbell I
Breast Cancer Res . 2004 Jun; 6(4):R390-4. PMID: 15217506
Background: Gene promoter methylation is an important regulator of expression and is a key epigenetic factor in tumorigenesis. DNA methylation is mediated by DNA methyltransferases (DNMTs), of which three active...