Minoru Morimoto
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Explore the profile of Minoru Morimoto including associated specialties, affiliations and a list of published articles.
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52
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566
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Recent Articles
1.
Identification of a Novel Deactivating Small-Molecule Compound for Fibrogenic Hepatic Stellate Cells
Sakaguchi T, Kono Y, Itaba N, Morimoto M, Isomoto H, Shiota G
Yonago Acta Med
. 2020 Mar;
63(1):79-87.
PMID: 32158337
Background: Liver fibrosis progresses to decompensated liver cirrhosis, for which medical needs remain unmet. We recently developed IC-2, a small-molecule compound that suppresses Wnt/β-catenin signaling, and found that IC-2 also...
2.
Hoi S, Tsuchiya H, Itaba N, Suzuki K, Oka H, Morimoto M, et al.
Clin Exp Pharmacol Physiol
. 2020 Feb;
47(6):940-946.
PMID: 32012313
Renal fibrosis compromises kidney function, and it is a risk factor for chronic kidney disease (CKD). CKD ultimately progresses to end-stage kidney disease that can be cured only by kidney...
3.
Izawa H, Kinai M, Ifuku S, Morimoto M, Saimoto H
Biomolecules
. 2019 Jul;
9(7).
PMID: 31284517
In order to synthesize a promising material for developing a novel peptide/protein delivery system, guanidinylation of chitooligosaccharides with 1-amidinopyrazole hydrochloride was investigated herein. The production of guanidinylated chitooligosaccharides was demonstrated...
4.
Itaba N, Sakabe T, Kanki K, Azumi J, Shimizu H, Kono Y, et al.
Regen Ther
. 2019 Jun;
2:32-41.
PMID: 31245457
Human mesenchymal stem cells (MSCs) are expected to have utility as a cell source in regenerative medicine. Because we previously reported that suppression of the Wnt/β-catenin signal enhances hepatic differentiation...
5.
Itaba N, Kono Y, Watanabe K, Yokobata T, Oka H, Osaki M, et al.
Sci Rep
. 2019 May;
9(1):6841.
PMID: 31048740
Chronic hepatitis viral infection, alcoholic intoxication, and obesity cause liver fibrosis, which progresses to decompensated liver cirrhosis, a disease for which medical demands cannot be met. Since there are currently...
6.
Azuma K, Koizumi R, Izawa H, Morimoto M, Saimoto H, Osaki T, et al.
Int J Biol Macromol
. 2018 Dec;
126:11-17.
PMID: 30576733
In this study, the effects of chitosan and surface-deacetylated chitin nanofibrils (SDACNFs) on hair growth were evaluated. In human follicle dermal papilla cells in vitro, chitosan and SDACNFs were shown...
7.
Izawa H, Kinai M, Ifuku S, Morimoto M, Saimoto H
Int J Biol Macromol
. 2018 Dec;
125:901-905.
PMID: 30572038
We introduce a simple method for producing guanidinylation of chitosan (CS) with 1‑amidinopyrazole hydrochloride (AP). Production of GCS is proved via NMR, IR, and elemental analyses. In a reaction using...
8.
Itaba N, Noda I, Oka H, Kono Y, Okinaka K, Yokobata T, et al.
Regen Ther
. 2018 Dec;
9:45-57.
PMID: 30525075
Introduction: We previously reported that transplantation of hepatic cell sheets from human bone marrow-derived mesenchymal stem cells (BM-MSCs) with hexachlorophene, a Wnt/β-catenin signaling inhibitor, ameliorated acute liver injury. In a...
9.
Azuma K, Izumi R, Osaki T, Ifuku S, Morimoto M, Saimoto H, et al.
J Funct Biomater
. 2018 Jun;
9(2).
PMID: 29880726
The Journal of Functional Biomaterials Editorial Office have been made aware that some parts of the article [1] are duplicated from other publications[...].
10.
Ifuku S, Nomura R, Morimoto M, Saimoto H
Materials (Basel)
. 2017 Aug;
4(8):1417-1425.
PMID: 28824151
Chitin nanofibers were isolated from the cell walls of five different types of mushrooms by the removal of glucans, minerals, and proteins, followed by a simple grinding treatment under acidic...