Mingxin Tang
Overview
Explore the profile of Mingxin Tang including associated specialties, affiliations and a list of published articles.
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20
Citations
615
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Recent Articles
1.
Bai Y, Zhang X, Li Y, Qi F, Liu C, Ai X, et al.
Circ Res
. 2024 Jan;
134(4):393-410.
PMID: 38275112
Background: The sympathoadrenergic system and its major effector PKA (protein kinase A) are activated to maintain cardiac output coping with physiological or pathological stressors. If and how PKA plays a...
2.
Li J, Fredericks M, Tang M, Cannell M, Joshi S, Kumar R, et al.
FEBS Lett
. 2022 Aug;
596(24):3145-3158.
PMID: 35920165
Cardiomyopathies are ascribed to a variety of etiologies, present with diverse clinical phenotypes, and lack disease-modifying treatments. Mounting evidence implicates dysregulated activin receptor signaling in heart disease and highlights inhibition...
3.
Liu J, Song Y, Tang M, Lu Q, Zhong G
J Hazard Mater
. 2020 Jun;
398:122954.
PMID: 32506048
The ubiquitous contamination generating from the frequent input of agrochemicals is a major hurdle affecting the ecological sustainability of agroecosystems. Here, we investigated the dissipation of multiple pesticides in the...
4.
Zhang Y, Wang W, Zhang X, Li Y, Chen B, Liu C, et al.
Circ Res
. 2019 Apr;
124(12):1760-1777.
PMID: 30982412
Rationale: PKA (Protein Kinase A) is a major mediator of β-AR (β-adrenergic) regulation of cardiac function, but other mediators have also been suggested. Reduced PKA basal activity and activation are...
5.
Li Z, Sun B, Gong T, Guo S, Zhang J, Wang J, et al.
Gastroenterology
. 2019 Mar;
156(8):2297-2312.
PMID: 30836096
Background & Aims: Interleukin 6 (IL6) and tumor necrosis factor contribute to the development of colitis-associated cancer (CAC). We investigated these signaling pathways and the involvement of G protein subunit...
6.
Williams A, Khadka V, Tang M, Avelar A, Schunke K, Menor M, et al.
Physiol Genomics
. 2018 Apr;
50(7):479-494.
PMID: 29652636
Alternative splicing of RNA is an underexplored area of transcriptional response. We expect that early changes in alternatively spliced genes may be important for responses to cardiac injury. Hypoxia inducible...
7.
Li Y, Zhang X, Zhang C, Zhang X, Li Y, Qi Z, et al.
J Physiol
. 2017 Dec;
596(7):1137-1151.
PMID: 29274077
Cav3.1 T-type Ca channel current (I ) contributes to heart rate genesis but is not known to contribute to heart rate regulation by the sympathetic/β-adrenergic system (SAS). We show that...
8.
Sun Z, Schriewer J, Tang M, Marlin J, Taylor F, Shohet R, et al.
J Mol Cell Cardiol
. 2015 Dec;
90:129-38.
PMID: 26686989
Elevated ALK4/5 ligands including TGF-β and activins have been linked to cardiovascular remodeling and heart failure. Doxorubicin (Dox) is commonly used as a model of cardiomyopathy, a condition that often...
9.
Zhang X, Ai X, Nakayama H, Chen B, Harris D, Tang M, et al.
Basic Res Cardiol
. 2015 Nov;
111(1):4.
PMID: 26611208
Persistent elevation of Ca(2+) influx due to prolongation of the action potential (AP), chronic activation of the β-adrenergic system and molecular remodeling occurs in stressed and diseased hearts. Increases in...
10.
Zhang X, Szeto C, Gao E, Tang M, Jin J, Fu Q, et al.
Circ Res
. 2012 Oct;
112(3):498-509.
PMID: 23104882
Rationale: In the failing heart, persistent β-adrenergic receptor activation is thought to induce myocyte death by protein kinase A (PKA)-dependent and PKA-independent activation of calcium/calmodulin-dependent kinase II. β-adrenergic signaling pathways...