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Minal Mane

Explore the profile of Minal Mane including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 12
Citations 72
Followers 0
Related Specialties
Biochemistry
General Medicine
Biology
Top 10 Co-Authors
Fatema Currim
Rajesh Singh
Anjali Shinde
Dhruv Gohel
Milton Roy
Jyoti Singh
Hitesh Vasiyani
Shatakshi Shukla
Kritarth Singh
Shanikumar Goyani
Published In
Apoptosis
Int J Biochem Cell Biol
Free Radic Biol Med
Int J Stem Cells
Mol Neurobiol
Affiliations
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Recent Articles
1.
Mitochondrial E3 ligase TRIM71 affects mitochondrial complex assembly and sensitizes dopaminergic neuronal cells to apoptosis in Parkinson's Disease (PD)
Goyani S, Shukla S, Mane M, Saranga M, Chandak N, Shinde A, et al.
Int J Biochem Cell Biol . 2024 Nov; 177:106689. PMID: 39522935
Parkinson's Disease (PD) is a chronic neurodegenerative disorder that impacts the substantia niagra region of the midbrain leading to impaired motor as well as non-motor symptoms of the central nervous...
2.
Neuronal exosomal miRNAs modulate mitochondrial functions and cell death in bystander neuronal cells under Parkinson's disease stress conditions
Currim F, Shukla S, Singh J, Gohel D, Mane M, Shinde A, et al.
Neurotoxicology . 2024 Feb; 101:102-116. PMID: 38401688
Parkinson's Disease (PD) is a chronic neurodegenerative disorder characterized by progressive loss of midbrain dopaminergic neurons in the substantia nigra part of the brain. Pathology spread to numerous brain regions...
3.
Enhanced translocation of TRIM32 to mitochondria sensitizes dopaminergic neuronal cells to apoptosis during stress conditions in Parkinson's disease
Goyani S, Shinde A, Shukla S, Saranga M, Currim F, Mane M, et al.
FEBS J . 2024 Feb; 291(12):2636-2655. PMID: 38317520
Parkinson's disease (PD) is a chronic neurodegenerative disease characterized by progressive loss of dopamine-producing neurons from the substantia nigra region of the brain. Mitochondrial dysfunction is one of the major...
4.
TNF-α induced NF-κB mediated LYRM7 expression modulates the tumor growth and metastatic ability in breast cancer
Shinde A, Chandak N, Singh J, Roy M, Mane M, Tang X, et al.
Free Radic Biol Med . 2023 Dec; 211:158-170. PMID: 38104742
Tumor microenvironment (TME) of solid tumors including breast cancer is complex and contains a distinct cytokine pattern including TNF-α, which determines the progression and metastasis of breast tumors. The metastatic...
5.
hsa-miR-320a mediated exosome release under PD stress conditions rescue mitochondrial ROS and cell death in the recipient neuronal and glial cells
Shukla S, Currim F, Singh J, Goyani S, Saranga M, Shinde A, et al.
Int J Biochem Cell Biol . 2023 Jul; 162:106439. PMID: 37429353
Parkinson's disease (PD) is a progressive neurodegenerative disorder characterized by dopaminergic neuronal cell death. Emerging evidence suggest exosomes as a crucial player in the progression and pathogenesis of PD via...
6.
DNA damage induces STING mediated IL-6-STAT3 survival pathway in triple-negative breast cancer cells and decreased survival of breast cancer patients
Vasiyani H, Mane M, Rana K, Shinde A, Roy M, Singh J, et al.
Apoptosis . 2022 Aug; 27(11-12):961-978. PMID: 36018392
Triple-negative breast cancer is aggressive and metastatic breast cancer type and shows immune evasion, drug resistance, relapse and poor survival. Anti-cancer therapy like ionizing radiation and chemotherapeutic drug majorly induces...
7.
TNF-α-induced E3 ligase, TRIM15 inhibits TNF-α-regulated NF-κB pathway by promoting turnover of K63 linked ubiquitination of TAK1
Roy M, Singh K, Shinde A, Singh J, Mane M, Bedekar S, et al.
Cell Signal . 2021 Dec; 91:110210. PMID: 34871740
Ubiquitin E3-ligases are recruited at different steps of TNF-α-induced NF-κB activation; however, their role in temporal regulation of the pathway remains elusive. The study systematically identified TRIMs as potential feedback...
8.
TNF-α differentially modulates subunit levels of respiratory electron transport complexes of ER/PR +ve/-ve breast cancer cells to regulate mitochondrial complex activity and tumorigenic potential
Shinde A, Jung H, Lee H, Singh K, Roy M, Gohel D, et al.
Cancer Metab . 2021 Apr; 9(1):19. PMID: 33926547
Background: Tumor necrosis factor-α (TNF-α) is an immunostimulatory cytokine that is consistently high in the breast tumor microenvironment (TME); however, its differential role in mitochondrial functions and cell survival in...
9.
The analog of cGAMP, c-di-AMP, activates STING mediated cell death pathway in estrogen-receptor negative breast cancer cells
Vasiyani H, Shinde A, Roy M, Mane M, Singh K, Singh J, et al.
Apoptosis . 2021 Apr; 26(5-6):293-306. PMID: 33840002
Immune adaptor protein like STING/MITA regulate innate immune response and plays a critical role in inflammation in the tumor microenvironment and regulation of metastasis including breast cancer. Chromosomal instability in...
10.
Expression of expanded FMR1-CGG repeats alters mitochondrial miRNAs and modulates mitochondrial functions and cell death in cellular model of FXTAS
Gohel D, Sripada L, Prajapati P, Currim F, Roy M, Singh K, et al.
Free Radic Biol Med . 2021 Jan; 165:100-110. PMID: 33497798
Fragile X-associated tremor/ataxia syndrome (FXTAS) is a progressive neurodegenerative disorder caused by an expansion of 55 to 200 CGG repeats located within 5'UTR of FMR1.These CGG repeats are transcribed into...