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Min D Tang-Schomer

Explore the profile of Min D Tang-Schomer including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 679
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Recent Articles
1.
Tang-Schomer M, Bookland M, Sargent J, N Jackvony T
Bioengineering (Basel) . 2023 Jul; 10(7). PMID: 37508868
Despite in vivo malignancy, ependymoma lacks cell culture models, thus limiting therapy development. Here, we used a tunable three-dimensional (3D) culture system to approximate the ependymoma microenvironment for recapitulating a...
2.
Tang-Schomer M, Chandok H, Wu W, Lau C, Bookland M, George J
Transl Oncol . 2022 Apr; 20:101407. PMID: 35381525
Brain tumors are the leading cause of cancer-related deaths in children. Tailored therapies need preclinical brain tumor models representing a wide range of molecular subtypes. Here, we adapted a previously...
3.
Jaiswal D, Tang-Schomer M, Sood D, Kaplan D, Hoshino K
ACS Biomater Sci Eng . 2021 Jan; 4(9):3259-3267. PMID: 33435062
We propose a novel nondestructive, label-free, mechanical characterization method for composite biomimetic materials. The method combines microscale-force measurement, bright-field microscopy based deformation analysis, and finite-element methods (FEM) to study the...
4.
Tang-Schomer M, Kaplan D, Whalen M
Acta Biomater . 2019 Mar; 94:306-319. PMID: 30836199
Brain access remains a major challenge in drug testing. The nearly 'impermeable' blood-brain-barrier (BBB) prevents most drugs from gaining access to brain cells via systematic intravenous (IV) injection. In this...
5.
Tang-Schomer M, Jackvony T, Santaniello S
Front Neurosci . 2018 Oct; 12:630. PMID: 30297981
Synchronous network activity plays a crucial role in complex brain functions. Stimulating the nervous system with applied electric field (EF) is a common tool for probing network responses. We used...
6.
Tang-Schomer M
Brain Res . 2017 Nov; 1678:288-296. PMID: 29097106
Axon growth and alignment are fundamental processes during nervous system development and neural regeneration after injury. The present study investigates the effects of exogenous stimulus of electrical signals and soluble...
7.
Chwalek K, Tang-Schomer M, Omenetto F, Kaplan D
Nat Protoc . 2015 Aug; 10(9):1362-73. PMID: 26270395
A bioengineered model of 3D brain-like tissue was developed using silk-collagen protein scaffolds seeded with primary cortical neurons. The scaffold design provides compartmentalized control for spatial separation of neuronal cell...
8.
Tang-Schomer M, Hu X, Tupaj M, Tien L, Whalen M, Omenetto F, et al.
Adv Funct Mater . 2014 Nov; 24(13):1938-1948. PMID: 25386113
Neural engineering provides promise for cell therapy by integrating the host brain with brain-machine-interface technologies in order to externally modulate functions. Long-term interfaces with the host brain remain a critical...
9.
Tang-Schomer M, White J, Tien L, Schmitt L, Valentin T, Graziano D, et al.
Proc Natl Acad Sci U S A . 2014 Aug; 111(38):13811-6. PMID: 25114234
The brain remains one of the most important but least understood tissues in our body, in part because of its complexity as well as the limitations associated with in vivo...
10.
Hu X, Tang-Schomer M, Huang W, Xia X, Weiss A, Kaplan D
Adv Funct Mater . 2014 Aug; 23(31):3875-3884. PMID: 25093018
Tunable protein composites are important for constructing extracellular matrix mimics of human tissues with control of biochemical, structural, and mechanical properties. Molecular interaction mechanisms between silk fibroin protein and recombinant...