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» Authors » Milton M Kanashiro

Milton M Kanashiro

Explore the profile of Milton M Kanashiro including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 16
Citations 101
Followers 0
Related Specialties
Biochemistry
Veterinary Medicine
Pathology
Top 10 Co-Authors
Christiane Fernandes
Adolfo Horn Jr
Jackson A L C Resende
Erika S Bull
Joao Carlos de A Almeida
Franz V Borges
Jorge H Petretski
Leide L F Maciel
Thereza L Kipnis
Samila R Morcelli
Published In
J Inorg Biochem
Biometals
Biochem Pharmacol
APMIS
J Comp Pathol
Affiliations
Soon will be listed here.
Recent Articles
1.
DNA methylation in regulatory elements of the FKBP5 and NR3C1 gene in mother-child binomials with depression
Mendonca M, Mangiavacchi P, Mendes A, Loureiro S, Martin-Santos R, Gloria L, et al.
J Affect Disord . 2023 Mar; 331:287-299. PMID: 36933666
Background: The FKBP5 and NR3C1 genes play an important role in stress response, thus impacting mental health. Stress factor exposure in early life, such as maternal depression, may contribute to...
2.
Antitumor activity via apoptotic cell death pathway of water soluble copper(II) complexes: effect of the diamino unit on selectivity against lung cancer NCI-H460 cell line
Terra W, Bull E, Morcelli S, Moreira R, Maciel L, Almeida J, et al.
Biometals . 2021 Apr; 34(3):661-674. PMID: 33813688
The cytotoxicity against five human tumor cell lines (THP-1, U937, Molt-4, Colo-205 and NCI-H460) of three water soluble copper(II) coordination compounds containing the ligands 3,3'-(ethane-1,2-diylbis(azanediyl))dipropanamide (BCEN), 3,3'-(piperazine-1,4-diyl)dipropanamide (BPAP) or 3,3'-and...
3.
Effect of the hydroxamate group in the antitumoral activity and toxicity toward normal cells of new copper(II) complexes
Azeredo N, Borges F, Mathias M, Resende J, Franco R, Kanashiro M, et al.
Biometals . 2021 Feb; 34(2):229-244. PMID: 33559811
The synthesis, physico-chemical characterization and cytotoxicity of four copper(II) coordination complexes, i.e. [Cu(HBPA)Cl] (1), [Cu(BHA)] (2), [Cu(HBPA)(BHA)Cl] CHOH (3) and [Cu(HBPA)]Cl·4HO (4), are reported. HBPA is the tridentate ligand N-(2-hydroxybenzyl)-N-(2-pyridylmethyl)amine...
4.
Cetacean Morbillivirus Infection in a Killer Whale (Orcinus orca) from Brazil
Groch K, Jerdy H, Marcondes M, Barbosa L, Ramos H, Pavanelli L, et al.
J Comp Pathol . 2020 Dec; 181:26-32. PMID: 33288147
We provide pathological, immunohistochemical and molecular evidence of cetacean morbillivirus (CeMV) infection in a live-stranded adult female killer whale (Orcinus orca), which stranded alive in Espírito Santo State, Brazil, in...
5.
Modulating the antitumoral activity by the design of new platinum(II) compounds: Synthesis, characterization, DFT, ultrastructure and mechanistic studies
Moreira R, Morcelli S, Kanashiro M, Resende J, Maciel L, Almeida J, et al.
J Inorg Biochem . 2019 Mar; 194:200-213. PMID: 30877895
The synthesis, physico-chemical characterization, Density functional theory (DFT) calculation and cytotoxicity against five human tumoral cell lines (THP-1, U937, Molt-4, Colo205 and H460) of four new platinum(II) coordination compounds are...
6.
In vitro and in vivo studies of the antineoplastic activity of copper (II) compounds against human leukemia THP-1 and murine melanoma B16-F10 cell lines
Borges L, Bull E, Fernandes C, Horn Jr A, Azeredo N, Resende J, et al.
Eur J Med Chem . 2016 Jul; 123:128-140. PMID: 27474929
We investigated the antineoplastic activities of a previously reported copper (II) coordination compound, [Cu(BMPA)Cl2]CH3OH (1), and a new compound, [Cu(HBPA)Cl2]H2O (2), where BMPA is bis(pyridin-2-ylmethyl)amine and HBPA is (2-hydroxybenzyl)(2-pyridylmethyl)amine, using...
7.
Synthesis, characterization and antitumoral activity of new cobalt(II)complexes: Effect of the ligand isomerism on the biological activity of the complexes
Morcelli S, Bull E, Terra W, Moreira R, Borges F, Kanashiro M, et al.
J Inorg Biochem . 2016 May; 161:73-82. PMID: 27221950
The synthesis, physico-chemical characterization and cytotoxicity against five human tumoral cell lines (THP-1, U937, Molt-4, Colo205 and H460) of three new cobalt(II) coordination compounds are reported (i.e. Co(HL1)Cl (1), Co(HL2)Cl...
8.
Induction of apoptosis in leukemia cell lines by new copper(II) complexes containing naphthyl groups via interaction with death receptors
Fernandes C, Horn Jr A, Lopes B, Bull E, Azeredo N, Kanashiro M, et al.
J Inorg Biochem . 2015 Oct; 153:68-87. PMID: 26485179
The synthesis, physico-chemical characterization and cytotoxicity of four new ligands and their respective copper(II) complexes toward two human leukemia cell lines (THP-1 and U937) are reported (i.e. [(HL1)Cu(μ-Cl)2Cu(HL1)]Cl2·H2O (1), [(H2L2)Cu(μ-Cl)2Cu(H2L2)]Cl2·5H2O...
9.
Lepidotrichilins A and B, new protolimonoids with cytotoxic activity from Trichilia lepidota (Meliaceae)
Terra W, Vieira I, Braz-Filho R, de Freitas W, Kanashiro M, Torres M
Molecules . 2013 Oct; 18(10):12180-91. PMID: 24084021
Two novel protolimonoids, named lepidotrichilins A (1) and B (2), four known protolimonoids, 21,23-epoxy-7α-21α-dihydroxyapotirucalla-14,24-dien-3-one (3), 21,23-epoxy-7α-21β-dihydroxyapotiru-calla-14,24-dien-3-one (4), dysorone D (5), deoxy-flindissone (6), and the two steroids β-sitosterol (7) and stigmasterol...
10.
Highly efficient synthetic iron-dependent nucleases activate both intrinsic and extrinsic apoptotic death pathways in leukemia cancer cells
Horn Jr A, Fernandes C, Parrilha G, Kanashiro M, Borges F, de Melo E, et al.
J Inorg Biochem . 2013 Aug; 128:38-47. PMID: 23933562
The nuclease activity and the cytotoxicity toward human leukemia cancer cells of iron complexes, [Fe(HPClNOL)Cl2]NO3 (1), [Cl(HPClNOL)Fe(μ-O)Fe(HPClNOL)Cl]Cl2·2H2O (2), and [(SO4)(HPClNOL)Fe(μ-O)Fe(HPClNOL)(SO4)]·6H2O (3) (HPClNOL=1-(bis-pyridin-2-ylmethyl-amino)-3-chloropropan-2-ol), were investigated. Each complex was able to promote...