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Mila Angert

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Articles 22
Citations 541
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Recent Articles
1.
Hullugundi S, Dolkas J, Chernov A, Yaksh T, Eddinger K, Angert M, et al.
Brain Behav Immun Health . 2024 Apr; 38:100757. PMID: 38590761
Background: A bioactive myelin basic protein (MBP) fragment, comprising MBP, is released in sciatic nerve after chronic constriction injury (CCI). Intraneural injection (IN) of MBP in an intact sciatic nerve...
2.
Chernov A, Hullugundi S, Eddinger K, Dolkas J, Remacle A, Angert M, et al.
J Biol Chem . 2020 Jun; 295(31):10807-10821. PMID: 32532796
In the peripheral nerve, mechanosensitive axons are insulated by myelin, a multilamellar membrane formed by Schwann cells. Here, we offer first evidence that a myelin degradation product induces mechanical hypersensitivity...
3.
Renaud L, Huff M, da Silveira W, Angert M, Haas M, Hardiman G
Curr Genomics . 2020 Feb; 20(4):260-274. PMID: 32030086
Methodology: In this study, healthy primary human prostate epithelial cells (PrECs) were exposed to environmentally relevant concentrations of BPA (5nM and 25nM BPA) and interrogated using a whole genome microarray....
4.
Chernov A, Remacle A, Hullugundi S, Cieplak P, Angert M, Dolkas J, et al.
FEBS J . 2018 Aug; 285(18):3485-3502. PMID: 30079618
Database: The novel RNA-seq datasets were deposited in the GEO database under the accession number GSE107020.
5.
Remacle A, Hullugundi S, Dolkas J, Angert M, Cieplak P, Scott D, et al.
Biochem J . 2018 Jun; 475(14):2355-2376. PMID: 29954845
In demyelinating nervous system disorders, myelin basic protein (MBP), a major component of the myelin sheath, is proteolyzed and its fragments are released in the neural environment. Here, we demonstrated...
6.
Remacle A, Hullugundi S, Dolkas J, Angert M, Chernov A, Strongin A, et al.
J Neuroinflammation . 2018 Mar; 15(1):89. PMID: 29558999
Background: In the peripheral nerve, pro-inflammatory matrix metalloproteinase (MMP)-9 performs essential functions in the acute response to injury. Whether MMP-9 activity contributes to late-phase injury or whether MMP-9 expression or...
7.
Remacle A, Dolkas J, Angert M, Hullugundi S, Chernov A, Jones 3rd R, et al.
J Immunol Methods . 2018 Feb; 455:80-87. PMID: 29428829
Sciatic nerve chronic constriction injury (CCI) in rodents produces nerve demyelination via proteolysis of myelin basic protein (MBP), the major component of myelin sheath. Proteolysis releases the cryptic MBP epitope,...
8.
Hong S, Remacle A, Shiryaev S, Choi W, Hullugundi S, Dolkas J, et al.
Brain Behav Immun . 2016 Nov; 60:282-292. PMID: 27833045
Myelin basic protein (MBP) is an auto-antigen able to induce intractable pain from innocuous mechanical stimulation (mechanical allodynia). The mechanisms provoking this algesic MBP activity remain obscure. Our present study...
9.
Ko J, Eddinger K, Angert M, Chernov A, Dolkas J, Strongin A, et al.
Brain Behav Immun . 2016 Mar; 56:378-89. PMID: 26970355
Mechanosensory fibers are enveloped by myelin, a unique multilamellar membrane permitting saltatory neuronal conduction. Damage to myelin is thought to contribute to severe pain evoked by innocuous tactile stimulation (i.e.,...
10.
Liu H, Dolkas J, Hoang K, Angert M, Chernov A, Remacle A, et al.
J Neuroinflammation . 2015 Sep; 12:158. PMID: 26337825
Background: Mechanical pain hypersensitivity associated with physical trauma to peripheral nerve depends on T-helper (Th) cells expressing the algesic cytokine, interleukin (IL)-17A. Fibronectin (FN) isoform alternatively spliced within the IIICS...