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Mikko P Pakarinen

Explore the profile of Mikko P Pakarinen including associated specialties, affiliations and a list of published articles. Areas
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Articles 200
Citations 1934
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Recent Articles
1.
Gnatzy R, Lacher M, Berger M, Boettcher M, Deffaa O, Kubler J, et al.
Eur J Pediatr Surg . 2025 Mar; PMID: 40043742
Introduction: The emergence of large language models (LLMs) has led to notable advancements across multiple sectors, including medicine. Yet, their effect in pediatric surgery remains largely unexplored. This study aims...
2.
Anderson L, Hukkinen M, Nyholm I, Niemi M, Pakarinen M
J Pediatr Gastroenterol Nutr . 2025 Mar; 80(3):462-470. PMID: 40028801
Objectives: To compare the predictive value of serum bile acids on native liver survival (NLS) and portal hypertension (PH) at various time points early after portoenterostomy (PE) in biliary atresia...
3.
Nyholm I, Hukkinen M, Lohi J, Sjoblom N, Mutka A, Mutanen A, et al.
J Hepatol . 2025 Jan; PMID: 39889904
Background & Aims: Little is known on the mechanism of liver injury mediated by bile acids following Kasai portoenterostomy (KPE) in biliary atresia (BA). We sought to quantify individual serum...
4.
Nyholm I, Hukkinen M, Pakarinen M
Semin Pediatr Surg . 2025 Jan; 33(6):151473. PMID: 39884181
Regardless of the underlying etiology and success of PE, progressive liver fibrosis and eventually cirrhosis represent the dominant pathology and the end-stage of BA. Ascending bile duct injury-induced cholestasis, inflammation...
5.
Pihlajoki M, Eloranta K, Nousiainen R, Vayrynen V, Soini T, Kyronlahti A, et al.
Adv Biol Regul . 2024 Nov; :100997. PMID: 39492287
Our research laboratory has a longstanding interest in developmental disorders and embryonic tumors, and recent efforts have focused on the pathogenesis of pediatric liver tumors. This review focuses on hepatoblastoma...
6.
Pakarinen M, Mutanen A
World J Pediatr Surg . 2024 Oct; 7(3):e000859. PMID: 39410940
Although patients with Hirschsprung disease are mostly affected by imperfect bowel function and fecal control in the long term, they are also predisposed to lower urinary tract symptoms, impaired sexual...
7.
Wong C, Koga H, Sugita K, Kato D, Mutanen A, Chung P, et al.
J Pediatr Surg . 2024 Aug; 60(2):161652. PMID: 39181779
Purpose: To analyze and compare the outcomes in patients with anorectal malformation with rectoprostatic and rectourethral fistula between laparoscopic-assisted anorectoplasty (LAARP) versus posterior sagittal anorectoplasty (PSARP). Method: We performed a...
8.
Pakarinen M, Luoto T, Nuutinen S, Raitio A, Tahkola E, Koivusalo A
J Pediatr Surg . 2024 Aug; 59(11):161642. PMID: 39142954
Aim Of The Study: Continuous surgical developments, growing awareness of patient representatives and limited health-care resources are pushing for innovative approaches to ensure equal high-quality pediatric surgical care. We aimed...
9.
Tahkola E, Luoto T, Pakarinen M
J Pediatr Surg . 2024 Aug; 59(11):161622. PMID: 39097495
Aim Of The Study: We aimed to evaluate disease characteristics, associated malformations and surgical outcomes of congenital intestinal atresia. Methods: We identified all patients with jejunoileal (JIA) or colonic atresia...
10.
Cullis P, Fouad D, Goldstein A, Wong K, Boonthai A, Lobos P, et al.
BJS Open . 2024 May; 8(3). PMID: 38776252
Background: In recent decades, the survival of children with congenital anomalies and paediatric cancer has improved dramatically such that there has been a steady shift towards understanding their lifelong health...