Miki Uesaka
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Explore the profile of Miki Uesaka including associated specialties, affiliations and a list of published articles.
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10
Citations
167
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Recent Articles
1.
Mizutani T, Orisaka M, Kawabe S, Morichika R, Uesaka M, Yoshida Y
Mol Cell Endocrinol
. 2022 Oct;
559:111808.
PMID: 36309205
Steroidogenesis in ovarian granulosa cells is regulated by the follicle-stimulating hormone (FSH) via transcriptional regulation of its related genes. We herein showed the involvement of the Hippo pathway in this...
2.
Mizutani T, Orisaka M, Miyazaki Y, Morichika R, Uesaka M, Miyamoto K, et al.
Mol Hum Reprod
. 2022 Aug;
28(10).
PMID: 35993908
During placentation, placental cytotrophoblast (CT) cells differentiate into syncytiotrophoblast (ST) cells and extravillous trophoblast (EVT) cells. In the placenta, the expression of various genes is regulated by the Hippo pathway...
3.
Klocko A, Uesaka M, Ormsby T, Rountree M, Wiles E, Adhvaryu K, et al.
Genetics
. 2018 Dec;
211(2):563-578.
PMID: 30554169
In the filamentous fungus , constitutive heterochromatin is marked by tri-methylation of histone H3 lysine 9 (H3K9me3) and DNA methylation. We identified mutations in the defective in methylation-1 () gene...
4.
Klocko A, Ormsby T, Galazka J, Leggett N, Uesaka M, Honda S, et al.
Proc Natl Acad Sci U S A
. 2016 Nov;
113(52):15048-15053.
PMID: 27856763
High-throughput chromosome conformation capture (Hi-C) analyses revealed that the 3D structure of the Neurospora crassa genome is dominated by intra- and interchromosomal links between regions of heterochromatin, especially constitutive heterochromatin....
5.
Galazka J, Klocko A, Uesaka M, Honda S, Selker E, Freitag M
Genome Res
. 2016 Jun;
26(8):1069-80.
PMID: 27260477
Eukaryotic genomes are organized into chromatin domains with three-dimensional arrangements that presumably result from interactions between the chromatin constituents-proteins, DNA, and RNA-within the physical constraints of the nucleus. We used...
6.
Mizutani T, Yazawa T, Ju Y, Imamichi Y, Uesaka M, Inaoka Y, et al.
J Biol Chem
. 2010 Jul;
285(36):28240-51.
PMID: 20601698
StAR (steroidogenic acute regulatory protein) mediates the transport of cholesterol from the outer to the inner mitochondrial membrane, the process of which is the rate-limiting step for steroidogenesis. Transcriptional regulation...
7.
Inaoka Y, Yazawa T, Mizutani T, Kokame K, Kangawa K, Uesaka M, et al.
Reprod Biol Endocrinol
. 2008 Dec;
6:62.
PMID: 19077323
Background: P450 oxidoreductase (POR) catalyzes electron transfer to microsomal P450 enzymes. Its deficiency causes Antley-Bixler syndrome (ABS), and about half the patients with ABS have ambiguous genitalia and/or impaired steroidogenesis....
8.
Inaoka Y, Yazawa T, Uesaka M, Mizutani T, Yamada K, Miyamoto K
Mol Reprod Dev
. 2008 Jan;
75(5):931-9.
PMID: 18163434
NR4A1, also called NGFI-B in the rat, Nur77 in the mouse and TR3 in humans, belongs to the orphan nuclear steroid hormone receptor superfamily and is one of the immediate-early...
9.
Yazawa T, Uesaka M, Inaoka Y, Mizutani T, Sekiguchi T, Kajitani T, et al.
Endocrinology
. 2007 Dec;
149(4):1786-92.
PMID: 18162527
We have shown previously that Cyp11b1, an 11beta-hydroxylase responsible for glucocorticoid biosynthesis in the adrenal gland, was induced by cAMP in androgen-producing Leydig-like cells derived from mesenchymal stem cells. We...
10.
Abe Y, Sinozaki H, Takagi T, Minegishi T, Kokame K, Kangawa K, et al.
Reprod Biol Endocrinol
. 2006 May;
4:27.
PMID: 16704738
Background: Exposure to dioxins results in a broad range of pathophysiological disorders in human fetuses. In order to evaluate the effects of dioxins on the feto-placental tissues, we analyzed the...