Mikhail I Dobrikov
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Explore the profile of Mikhail I Dobrikov including associated specialties, affiliations and a list of published articles.
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Articles
19
Citations
213
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Recent Articles
1.
Dobrikov M, Dobrikova E, Nardone-White D, McKay Z, Brown M, Gromeier M
mBio
. 2023 Nov;
14(6):e0191523.
PMID: 37962360
Multiple pattern recognition receptors sense vRNAs and initiate downstream innate signaling: endosomal Toll-like receptors (TLRs) 3, 7, and 8 and cytoplasmic RIG-I-like receptors (RLRs) RIG-I, and MDA5. They engage distinct...
2.
Dobrikov M, Dobrikova E, McKay Z, Kastan J, Brown M, Gromeier M
mBio
. 2022 Jun;
13(3):e0085422.
PMID: 35652592
For RNA virus families except , viral RNA sensing includes Toll-like receptors and/or RIG-I. Picornavirus RNAs, whose 5' termini are shielded by a genome-linked protein, are predominately recognized by MDA5....
3.
Kastan J, Tremblay M, Brown M, Trimarco J, Dobrikova E, Dobrikov M, et al.
mBio
. 2021 Apr;
12(2).
PMID: 33849973
Enteroviruses (EV) deploy two proteases that mediate viral polyprotein cleavage and host cell manipulation. Here, we report that EV 2A proteases cleave all three members of the YTHDF protein family,...
4.
Mosaheb M, Brown M, Dobrikova E, Dobrikov M, Gromeier M
Curr Opin Virol
. 2020 Aug;
44:73-80.
PMID: 32771959
Dendritic cells (DCs) are pivotal stimulators of T cell responses. They provide essential signals (epitope presentation, proinflammatory cytokines, co-stimulation) to T cells and prime adaptive immunity. Therefore, they are paramount...
5.
Dobrikov M, Dobrikova E, Gromeier M
Mol Cell Biol
. 2018 Jul;
38(19).
PMID: 30012864
The receptor for activated C kinase (RACK1), a conserved constituent of eukaryotic ribosomes, mediates phosphorylation of eukaryotic initiation factor 4G1(S1093) [eIF4G1(S1093)] and eIF3a(S1364) by protein kinase C βII (PKCβII) (M....
6.
Dobrikov M, Dobrikova E, Gromeier M
Mol Cell Biol
. 2018 Jul;
38(19).
PMID: 30012863
Eukaryotic ribosomes contain the high-affinity protein kinase C βII (PKCβII) scaffold, receptor for activated C kinase (RACK1), but its role in protein synthesis control remains unclear. We found that RACK1:PKCβII...
7.
Bryant J, Brown M, Dobrikov M, Dobrikova E, Gemberling S, Zhang Q, et al.
Mol Cell Biol
. 2018 Mar;
38(11).
PMID: 29530922
Death-associated protein 5 (DAP5) is an atypical isoform of the translation initiation scaffolds eukaryotic initiation factor 4GI (eIF4GI) and eIF4GII (eIF4GI/II), which recruit mRNAs to ribosomes in mammals. Unlike eIF4GI/II,...
8.
Brown M, Dobrikov M, Gromeier M
J Virol
. 2014 Sep;
88(22):13149-60.
PMID: 25187540
Unlabelled: Translation machinery is a major recipient of the principal mitogenic signaling networks involving Raf-ERK1/2 and phosphoinositol 3-kinase (PI3K)-mechanistic target of rapamycin (mTOR). Picornavirus internal ribosomal entry site (IRES)-mediated translation...
9.
Brown M, Dobrikova E, Dobrikov M, Walton R, Gemberling S, Nair S, et al.
Cancer
. 2014 Jun;
120(21):3277-86.
PMID: 24939611
Recently, the century-old idea of targeting cancer with viruses (oncolytic viruses) has come of age, and promise has been documented in early stage and several late-stage clinical trials in a...
10.
Dobrikov M, Shveygert M, Brown M, Gromeier M
Mol Cell Biol
. 2013 Nov;
34(3):439-51.
PMID: 24248602
During mitosis, global translation is suppressed, while synthesis of proteins with vital mitotic roles must go on. Prior evidence suggests that the mitotic translation shift involves control of initiation. Yet,...