Mike Partridge
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Explore the profile of Mike Partridge including associated specialties, affiliations and a list of published articles.
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61
Citations
1581
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Recent Articles
1.
Paczkowski M, Kretzschmar W, Markelc B, Liu S, Kunz-Schughart L, Harris A, et al.
Commun Biol
. 2021 Jan;
4(1):6.
PMID: 33398023
Intratumoural heterogeneity (ITH) contributes to local recurrence following radiotherapy in prostate cancer. Recent studies also show that ecological interactions between heterogeneous tumour cell populations can lead to resistance in chemotherapy....
2.
Holyoake D, Partridge M, Hawkins M
Radiother Oncol
. 2019 May;
138:38-44.
PMID: 31136961
Introduction: The limited radiation tolerance of the small-bowel causes toxicity for patients receiving conventionally-fractionated radiotherapy for rectal cancer. Safe radiotherapy dose-escalation will require a better understanding of such toxicity. We...
3.
Kannan P, Kretzschmar W, Winter H, Warren D, Bates R, Allen P, et al.
Clin Cancer Res
. 2018 Jul;
24(19):4694-4704.
PMID: 29959141
Tumor vessels influence the growth and response of tumors to therapy. Imaging vascular changes using dynamic contrast-enhanced MRI (DCE-MRI) has shown potential to guide clinical decision making for treatment. However,...
4.
Warren S, Hurt C, Crosby T, Partridge M, Hawkins M
Int J Radiat Oncol Biol Phys
. 2017 Dec;
99(3):729-737.
PMID: 29280467
Purpose: Radiation therapy dose escalation using a simultaneous integrated boost (SIB) is predicted to improve local tumor control in esophageal cancer; however, any increase in acute hematologic toxicity (HT) could...
5.
Puri T, Greenhalgh T, Wilson J, Franklin J, Wang L, Strauss V, et al.
EJNMMI Res
. 2017 Sep;
7(1):78.
PMID: 28933018
Background: There is an increasing interest in developing predictive biomarkers of tissue hypoxia using functional imaging for personalised radiotherapy in patients with rectal cancer that are considered for neoadjuvant chemoradiotherapy...
6.
Grimes D, Warren D, Partridge M
Sci Rep
. 2017 Aug;
7(1):9781.
PMID: 28852130
Charged particles such as protons and carbon ions are an increasingly important tool in radiotherapy. There are however unresolved physics issues impeding optimal implementation, including estimation of dose deposition in...
7.
Holyoake D, Aznar M, Mukherjee S, Partridge M, Hawkins M
Radiother Oncol
. 2017 Jun;
123(3):431-437.
PMID: 28600084
Background And Purpose: Gastro-intestinal toxicity is dose-limiting in abdominal radiotherapy and correlated with duodenum dose-volume parameters. We aimed to derive updated NTCP model parameters using published data and prospective radiotherapy...
8.
Warren D, Partridge M
Phys Med Biol
. 2016 Nov;
61(24):8596-8624.
PMID: 27880734
Positron emission tomography (PET) using F-fluoromisonidazole (FMISO) is a promising technique for imaging tumour hypoxia, and a potential target for radiotherapy dose-painting. However, the relationship between FMISO uptake and oxygen...
9.
OConnor J, Aboagye E, Adams J, Aerts H, Barrington S, Beer A, et al.
Nat Rev Clin Oncol
. 2016 Oct;
14(3):169-186.
PMID: 27725679
Imaging biomarkers (IBs) are integral to the routine management of patients with cancer. IBs used daily in oncology include clinical TNM stage, objective response and left ventricular ejection fraction. Other...
10.
Ramroth J, Cutter D, Darby S, Higgins G, McGale P, Partridge M, et al.
Int J Radiat Oncol Biol Phys
. 2016 Sep;
96(4):736-747.
PMID: 27639294
Purpose: The optimum dose and fractionation in radiation therapy of curative intent for non-small cell lung cancer remains uncertain. We undertook a published data meta-analysis of randomized trials to examine...