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» Authors » Miia Valkonen

Miia Valkonen

Explore the profile of Miia Valkonen including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 29
Citations 460
Followers 0
Related Specialties
Critical Care
General Medicine
Anesthesiology
Top 10 Co-Authors
Jordi Rello
Peter Pickkers
Ville Pettila
Andreas Barratt-Due
Andry van de Louw
Marcio Soares
Elie Azoulay
Massimo Antonelli
Gaston Burghi
Djamel Mokart
Published In
Genome Announc
Intensive Care Med
Acta Anaesthesiol Scand
J Crit Care
Duodecim
Affiliations
Soon will be listed here.
Recent Articles
1.
Are contemporary antifungal doses sufficient for critically ill patients? Outcomes from an international, multicenter pharmacokinetics study for Screening Antifungal Exposure in Intensive Care Units-the SAFE-ICU study
Roberts J, Sime F, Lipman J, Hernandez-Mitre M, Baptista J, Bruggemann R, et al.
Intensive Care Med . 2025 Feb; 51(2):302-317. PMID: 39899034
Purpose: Appropriate antifungal therapy is a major determinant of survival in critically ill patients with invasive fungal disease. We sought to describe whether contemporary dosing of antifungals achieves therapeutic exposures...
2.
Fluid bolus increases plasma hyaluronan concentration compared to follow-up strategy without a bolus in oliguric intensive care unit patients
Serlo M, Inkinen N, Lakkisto P, Valkonen M, Pulkkinen A, Selander T, et al.
Sci Rep . 2024 Sep; 14(1):20808. PMID: 39242877
Fluid therapy is a fundamental part of supportive therapy in critical care. However, it is also a suspected risk for endothelial glycocalyx degradation which is associated with poor clinical outcomes....
3.
A protocol for an international, multicentre pharmacokinetic study for Screening Antifungal Exposure in Intensive Care Units: The SAFE-ICU study
Roberts J, Sime F, Lipman J, Hernandez-Mitre M, Baptista J, Bruggemann R, et al.
Crit Care Resusc . 2023 Oct; 25(1):1-5. PMID: 37876989
Objective: To describe whether contemporary dosing of antifungal drugs achieves therapeutic exposures in critically ill patients that are associated with optimal outcomes. Adequate antifungal therapy is a key determinant of...
4.
Non-interventional follow-up versus fluid bolus in RESPONSE to oliguria in hemodynamically stable critically ill patients: a randomized controlled pilot trial
Inkinen N, Pettila V, Valkonen M, Serlo M, Backlund M, Hastbacka J, et al.
Crit Care . 2022 Dec; 26(1):401. PMID: 36550559
Background: Fluid bolus therapy is a common intervention to improve urine output. Data concerning the effect of a fluid bolus on oliguria originate mainly from observational studies and remain controversial...
5.
End of life decisions in immunocompromised patients with acute respiratory failure
Burghi G, Metaxa V, Pickkers P, Soares M, Rello J, Bauer P, et al.
J Crit Care . 2022 Sep; 72:154152. PMID: 36137351
Purpose: To identify patient, disease and organizational factors associated with decisions to forgo life-sustaining therapies (DFLSTs) in critically ill immunocompromised patients admitted to the intensive care unit (ICU) for acute...
6.
Acute respiratory failure in immunocompromised patients: outcome and clinical features according to neutropenia status
Mokart D, Darmon M, Schellongowski P, Pickkers P, Soares M, Rello J, et al.
Ann Intensive Care . 2020 Oct; 10(1):146. PMID: 33090310
Background: The impact of neutropenia in critically ill immunocompromised patients admitted in a context of acute respiratory failure (ARF) remains uncertain. The primary objective was to assess the prognostic impact...
7.
ICU-acquired pneumonia in immunosuppressed patients with acute hypoxemic respiratory failure: A post-hoc analysis of a prospective international cohort study
Martin-Loeches I, Darmon M, Demoule A, Antonelli M, Schellongowski P, Pickkers P, et al.
J Crit Care . 2020 Oct; 63:243-245. PMID: 33012580
Objective: Intensive Care Units (ICU) acquired Pneumonia (ICU-AP) is one of the most frequent nosocomial infections in critically ill patients. Our aim was to determine the effects of having an...
8.
Continuous intravenous infusion of enoxaparin controls thrombin formation more than standard subcutaneous administration in critically ill patients. A sub-study of the ENOKSI thromboprophylaxis RCT
Vahtera A, Szanto T, Lassila R, Valkonen M, Sivula M, Huhtala H, et al.
Acta Anaesthesiol Scand . 2020 Sep; 65(1):109-115. PMID: 32888192
Introduction: Standard subcutaneous low-molecular-weight heparin (LMWH) thromboprophylaxis yields low anti-factor Xa activity in patients in the intensive care unit (ICU). The aim of the study was to assess coagulation status...
9.
Respiratory Mechanics and Outcomes in Immunocompromised Patients With ARDS: A Secondary Analysis of the EFRAIM Study
Demoule A, Antonelli M, Schellongowski P, Pickkers P, Soares M, Meyhoff T, et al.
Chest . 2020 Jun; 158(5):1947-1957. PMID: 32569634
Background: In view of the high mortality rate of immunocompromised patients with ARDS, it is important to identify targets for improvement. Research Question: This study investigated factors associated with mortality...
10.
Etiologies and Outcomes of Acute Respiratory Failure in Solid Organ Transplant Recipients: Insight Into the EFRAIM Multicenter Cohort
Messika J, Darmon M, Mal H, Pickkers P, Soares M, Canet E, et al.
Transplant Proc . 2020 Jun; 52(10):2980-2987. PMID: 32499142
Background: Respiratory complications of solid organ transplant (SOT) are a diagnostic and therapeutic challenge when requiring intensive care unit (ICU) admission. We aimed at describing this challenge in a prospective...