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Mihael Lazebnik

Explore the profile of Mihael Lazebnik including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Bailey-Hytholt C, Ulinski G, Dugas J, Haines M, Lazebnik M, Piepenhagen P, et al.
Curr Pharm Biotechnol . 2023 Apr; PMID: 37016519
Introduction: Lipid nanoparticles (LNPs) are one of the most clinically advanced candidates for delivering nucleic acids to target cell populations, such as hepatocytes. Once LNPs are endocytosed, they must release...
2.
Lazebnik M, Pack D
J Control Release . 2017 Jan; 247:19-27. PMID: 28043862
Design of safe and effective synthetic nucleic acid delivery vectors such as polycation/DNA or polycation/siRNA complexes (polyplexes) will be facilitated by quantitative understanding of the mechanisms by which such materials...
3.
Lazebnik M, Keswani R, Pack D
Pharm Res . 2016 Sep; 33(12):2999-3011. PMID: 27585903
Purpose: siRNA may be delivered as electrostatic complexes with cationic lipids (lipoplexes) or polycations (polyplexes). The purpose of this project was to determine the effect of cellular internalization mechanism(s) on...
4.
Keswani R, Lazebnik M, Pack D
J Control Release . 2015 Apr; 207:120-30. PMID: 25883029
Viral and non-viral gene delivery vectors are in development for human gene therapy, but both exhibit disadvantages such as inadequate efficiency, lack of cell-specific targeting or safety concerns. We have...
5.
Lazebnik M, Singh M, Glatt P, Friis L, Berkland C, Detamore M
J Tissue Eng Regen Med . 2011 Jul; 5(8):e179-87. PMID: 21774081
Tissue engineering strategies for the intervertebral disc (IVD) have traditionally focused either on the annulus fibrosus (AF) or the nucleus pulposus (NP) in isolation, or have simply compared AF cells...