Miha Kosmac
Overview
Explore the profile of Miha Kosmac including associated specialties, affiliations and a list of published articles.
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8
Citations
145
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0
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Recent Articles
1.
Hutchison W, Keyes T, Crowell H, Serizay J, Soneson C, Davis E, et al.
Nat Methods
. 2024 Jun;
21(7):1166-1170.
PMID: 38877315
The growth of omic data presents evolving challenges in data manipulation, analysis and integration. Addressing these challenges, Bioconductor provides an extensive community-driven biological data analysis platform. Meanwhile, tidy R programming...
2.
Hutchison W, Keyes T, Crowell H, Serizay J, Soneson C, Davis E, et al.
bioRxiv
. 2024 Jun;
PMID: 38826347
The growth of omic data presents evolving challenges in data manipulation, analysis, and integration. Addressing these challenges, Bioconductor provides an extensive community-driven biological data analysis platform. Meanwhile, tidy R programming...
3.
Richardson E, Binter S, Kosmac M, Ghraichy M, von Niederhausern V, Kovaltsuk A, et al.
Elife
. 2023 Mar;
12.
PMID: 36971345
Immunoglobulin loci-transgenic animals are widely used in antibody discovery and increasingly in vaccine response modelling. In this study, we phenotypically characterised B-cell populations from the Intelliselect Transgenic mouse (Kymouse) demonstrating...
4.
Sainson R, Thotakura A, Kosmac M, Borhis G, Parveen N, Kimber R, et al.
Cancer Immunol Res
. 2020 Oct;
8(12):1568-1582.
PMID: 32999002
The immunosuppressive tumor microenvironment constitutes a significant hurdle to immune checkpoint inhibitor responses. Both soluble factors and specialized immune cells, such as regulatory T cells (Treg), are key components of...
5.
Lee E, Liang Q, Ali H, Bayliss L, Beasley A, Bloomfield-Gerdes T, et al.
Nat Biotechnol
. 2014 Mar;
32(4):356-63.
PMID: 24633243
If immunized with an antigen of interest, transgenic mice with large portions of unrearranged human immunoglobulin loci can produce fully human antigen-specific antibodies; several such antibodies are in clinical use....
6.
Kosmac M, Koren S, Giachin G, Stoilova T, Gennaro R, Legname G, et al.
Mol Immunol
. 2010 Dec;
48(5):746-50.
PMID: 21176851
Monoclonal antibodies (mAbs) against prion proteins (PrPs) are indispensable in research and diagnosis of prion diseases, however the majority of these bind both the cellular (PrP(C)) and the disease-associated (PrP(Sc))...
7.
Kosmac M, Avcin T, Toplak N, Simonini G, Cimaz R, Serbec V
Pediatr Res
. 2010 Dec;
69(3):243-8.
PMID: 21131896
Over the past decade, the treatment of a variety of immune-mediated diseases has improved greatly due to the introduction of biologics for therapies in cases that are nonresponsive to traditional...
8.
Koren S, Kosmac M, Venturini A, Montanic S, Serbec V
Appl Microbiol Biotechnol
. 2008 Mar;
78(6):1071-8.
PMID: 18320189
Cross-contamination and misidentification of various cell lines is a widespread problem that can lead to spurious scientific conclusions. DNA fingerprinting is a powerful identification technique, which can be effectively used...