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Miguel Lopez-Lazaro

Explore the profile of Miguel Lopez-Lazaro including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 81
Citations 1869
Followers 0
Related Specialties
Oncology
Chemistry
Biochemistry
Top 10 Co-Authors
Jose Manuel Calderon-Montano
Estefania Burgos-Moron
Manuel Luis Orta
Nuria Pastor
Julio Jose Jimenez-Alonso
Emilio Guillen-Mancina
Santiago Mateos
Caroline A Austin
Victor Jimenez-Gonzalez
Felipe Cortes
Published In
Oncoscience
Eur J Med Chem
Int J Cancer
Nutrients
Int J Mol Sci
Affiliations
Soon will be listed here.
Recent Articles
1.
A quality-by-design approach for optimizing the functionalization of gold nanoparticles onto the surface of doxorubicin-encapsulated liposomes
Torres J, Calderon-Montano J, Prieto-Dapena F, Lopez-Lazaro M, Rueda M, Rabasco-Alvarez A, et al.
Int J Pharm . 2024 Dec; 669():125040. PMID: 39653291
Stimulus-responsive liposomes (L) are increasingly recognized for their potential in enhancing therapies, especially in cancer nanomedicine, owing to their ability to encapsulate drugs of diverse properties efficiently. In this study,...
2.
A Diet Lacking Selenium, but Not Zinc, Copper or Manganese, Induces Anticancer Activity in Mice with Metastatic Cancers
Diaz-Ortega P, Calderon-Montano J, Jimenez-Alonso J, Guillen-Mancina E, Jimenez-Gonzalez V, Burgos-Moron E, et al.
Nutrients . 2024 Jul; 16(14). PMID: 39064692
Selenium, zinc, copper, and manganese are essential components of antioxidant enzymes involved in the elimination of reactive oxygen species (ROS). Given that cancer cells produce high levels of ROS and...
3.
Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells
Guillen-Mancina E, Garcia-Lozano M, Burgos-Moron E, Mazzotta S, Martinez-Aguado P, Calderon-Montano J, et al.
Int J Mol Sci . 2023 Dec; 24(23). PMID: 38069364
Breast cancer is the most common type of cancer in women. Although current treatments can increase patient survival, they are rarely curative when the disease is advanced (metastasis). Therefore, there...
4.
Evaluation of Anticancer Activity of 76 Plant Species Collected in Andalusia (Spain) against Lung Cancer Cells
Jimenez-Gonzalez V, Benitez G, Pastor J, Lopez-Lazaro M, Calderon-Montano J
Plants (Basel) . 2023 Sep; 12(18). PMID: 37765439
Every year, cancer kills millions of people around the world. Finding more selective anticancer agents is essential to improve the low survival rates of patients with metastatic cancers. Since the...
5.
Dietary Manipulation of Amino Acids for Cancer Therapy
Jimenez-Alonso J, Lopez-Lazaro M
Nutrients . 2023 Jul; 15(13). PMID: 37447206
Cancer cells cannot proliferate and survive unless they obtain sufficient levels of the 20 proteinogenic amino acids (AAs). Unlike normal cells, cancer cells have genetic and metabolic alterations that may...
6.
Artificial Diets with Altered Levels of Sulfur Amino Acids Induce Anticancer Activity in Mice with Metastatic Colon Cancer, Ovarian Cancer and Renal Cell Carcinoma
Jimenez-Alonso J, Guillen-Mancina E, Calderon-Montano J, Jimenez-Gonzalez V, Diaz-Ortega P, Burgos-Moron E, et al.
Int J Mol Sci . 2023 Mar; 24(5). PMID: 36902018
Sulfur-containing amino acids methionine (Met), cysteine (Cys) and taurine (Tau) are common dietary constituents with important cellular roles. Met restriction is already known to exert in vivo anticancer activity. However,...
7.
Artificial Diets with Selective Restriction of Amino Acids and Very Low Levels of Lipids Induce Anticancer Activity in Mice with Metastatic Triple-Negative Breast Cancer
Guillen-Mancina E, Jimenez-Alonso J, Calderon-Montano J, Jimenez-Gonzalez V, Diaz-Ortega P, Burgos-Moron E, et al.
Cancers (Basel) . 2023 Mar; 15(5). PMID: 36900331
Patients with metastatic triple negative breast cancer (TNBC) need new therapies to improve the low survival rates achieved with standard treatments. In this work, we show for the first time...
8.
Manipulation of Amino Acid Levels with Artificial Diets Induces a Marked Anticancer Activity in Mice with Renal Cell Carcinoma
Calderon-Montano J, Guillen-Mancina E, Jimenez-Alonso J, Jimenez-Gonzalez V, Burgos-Moron E, Mate A, et al.
Int J Mol Sci . 2022 Dec; 23(24). PMID: 36555771
Targeted therapies with antiangiogenic drugs (e.g., sunitinib) and immune checkpoint inhibitors (e.g., anti-PD-1 antibodies) are the standard of care for patients with metastatic renal cell carcinoma. Although these treatments improve...
9.
Artificial Diets Based on Selective Amino Acid Restriction versus Capecitabine in Mice with Metastatic Colon Cancer
Jimenez-Alonso J, Guillen-Mancina E, Calderon-Montano J, Jimenez-Gonzalez V, Diaz-Ortega P, Burgos-Moron E, et al.
Nutrients . 2022 Aug; 14(16). PMID: 36014884
New therapies are needed to improve the low survival rates of patients with metastatic colon cancer. Evidence suggests that amino acid (AA) restriction can be used to target the altered...
10.
Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes
Carrasco C, Montilla F, Alvarez E, Calderon-Montano J, Lopez-Lazaro M, Galindo A
J Inorg Biochem . 2022 Jul; 235:111924. PMID: 35841721
Complexes Na[Ag(NHC)], 2a-e and 2b'-c', where NHC is a N-heterocyclic carbene of the 2,2'-(1H-2λ,3λ-imidazole-1,3-diyl)dicarboxylate type, were prepared by treatment of compounds HL, 1a-e and 1b'-c' (2-(1-(carboxyalkyl)-1H-imidazol-3-ium-3-yl)carboxylate), with silver oxide in...