Miguel Castilho
Overview
Explore the profile of Miguel Castilho including associated specialties, affiliations and a list of published articles.
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Articles
56
Citations
733
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Recent Articles
1.
Stoecker L, Cedillo-Servin G, Konig N, de Graaf F, Garcia-Jimenez M, Hofmann S, et al.
Adv Mater
. 2025 Jan;
37(10):e2410292.
PMID: 39871647
Current challenges in tissue engineering include creation of extracellular environments that support and interact with cells using biochemical, mechanical, and structural cues. Spatial control over these cues is currently limited...
2.
Valverde M, Stampa Zamorano C, Kozinec D, Benito Zarza L, van Genderen A, Janssen R, et al.
Adv Healthc Mater
. 2024 Nov;
14(1):e2401800.
PMID: 39511873
A novel approach merging melt electrowriting (MEW) with matched die thermoforming to achieve scaffolds with micron-sized curvatures (200 - 800 µm versus 1000 µm of mandrel printing) for in vitro...
3.
Viola M, Cedillo-Servin G, van Genderen A, Imhof I, Vena P, Mihajlovic M, et al.
Biomater Sci
. 2024 Sep;
12(20):5225-5238.
PMID: 39229829
Despite extensive research, current methods for creating three-dimensional (3D) silk fibroin (SF) scaffolds lack control over molecular rearrangement, particularly in the formation of β-sheet nanocrystals that severely embrittle SF, as...
4.
Janssen J, Chirico N, Ainsworth M, Cedillo-Servin G, Viola M, Dokter I, et al.
Biomater Sci
. 2024 Jun;
12(15):3866-3881.
PMID: 38910521
Cardiac tissue engineering (cTE) has already advanced towards the first clinical trials, investigating safety and feasibility of cTE construct transplantation in failing hearts. However, the lack of well-established preservation methods...
5.
Niknezhad S, Mehrali M, Khorasgani F, Heidari R, Kadumudi F, Golafshan N, et al.
Bioact Mater
. 2024 Jun;
38:540-558.
PMID: 38872731
Bacteria can be programmed to deliver natural materials with defined biological and mechanical properties for controlling cell growth and differentiation. Here, we present an elastic, resilient and bioactive polysaccharide derived...
6.
Rosales R, Mountris K, Olivan-Viguera A, Perez-Zabalza M, Cedillo-Servin G, Iglesias-Garcia O, et al.
Comput Biol Med
. 2024 Feb;
171:108044.
PMID: 38335818
Engineered heart tissues (EHTs) built from human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) showed promising results for cardiac function restoration following myocardial infarction. Nevertheless, human iPSC-CMs have longer action potential...
7.
Viola M, Ainsworth M, Mihajlovic M, Cedillo-Servin G, van Steenbergen M, van Rijen M, et al.
Biomacromolecules
. 2024 Feb;
25(3):1563-1577.
PMID: 38323427
Hydrogels are ideal materials to encapsulate cells, making them suitable for applications in tissue engineering and regenerative medicine. However, they generally do not possess adequate mechanical strength to functionally replace...
8.
Flosdorf N, Bohnke J, de Toledo M, Lutterbach N, Lerma V, Grasshoff M, et al.
Stem Cell Reports
. 2024 Jan;
19(2):224-238.
PMID: 38278152
The myeloproliferative disease polycythemia vera (PV) driven by the JAK2 V617F mutation can transform into myelofibrosis (post-PV-MF). It remains an open question how JAK2 V617F in hematopoietic stem cells induces...
9.
de Ruijter M, Diloksumpan P, Dokter I, Brommer H, Smit I, Levato R, et al.
Bioeng Transl Med
. 2024 Jan;
9(1):e10614.
PMID: 38193127
In articular cartilage (AC), the collagen arcades provide the tissue with its extraordinary mechanical properties. As these structures cannot be restored once damaged, functional restoration of AC defects remains a...
10.
Cedillo-Servin G, Louro A, Gamelas B, Meliciano A, Zijl A, Alves P, et al.
Biomater Adv
. 2023 Nov;
155:213692.
PMID: 37952463
Extracellular vesicle (EV)-based approaches for promoting angiogenesis have shown promising results. Yet, further development is needed in vehicles that prolong EV exposure to target organs. Here, we hypothesized that microfiber-reinforced...