Miguel Angel Peinado
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Explore the profile of Miguel Angel Peinado including associated specialties, affiliations and a list of published articles.
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11
Citations
378
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Recent Articles
1.
Tao Y, Kang B, Petkovich D, Bhandari Y, In J, Stein-OBrien G, et al.
Cancer Cell
. 2019 Feb;
35(2):315-328.e6.
PMID: 30753828
We addressed the precursor role of aging-like spontaneous promoter DNA hypermethylation in initiating tumorigenesis. Using mouse colon-derived organoids, we show that promoter hypermethylation spontaneously arises in cells mimicking the human...
2.
Prieto P, Jaen R, Calle D, Gomez-Serrano M, Nunez E, Fernandez-Velasco M, et al.
World J Gastroenterol
. 2019 Feb;
25(4):433-446.
PMID: 30700940
Background: Colorectal cancer (CRC) is the second most common cause of cancer death worldwide. It is broadly described that cyclooxygenase-2 (COX-2) is mainly overexpressed in CRC but less is known...
3.
Ejarque M, Ceperuelo-Mallafre V, Serena C, Pachon G, Nunez-Alvarez Y, Terron-Puig M, et al.
Cell Death Dis
. 2017 May;
8(5):e2802.
PMID: 28518147
Adipose tissue (AT) has a central role in obesity-related metabolic imbalance through the dysregulated production of cytokines and adipokines. In addition to its known risk for cardiovascular disease and diabetes,...
4.
Mancikova V, Buj R, Castelblanco E, Inglada-Perez L, Diez A, de Cubas A, et al.
Int J Cancer
. 2014 Jan;
135(3):598-610.
PMID: 24382797
Thyroid cancer is a heterogeneous disease with several subtypes characterized by cytological, histological and genetic alterations, but the involvement of epigenetics is not well understood. Here, we investigated the role...
5.
Gomez-Diaz E, Jorda M, Peinado M, Rivero A
PLoS Pathog
. 2012 Dec;
8(11):e1003007.
PMID: 23209403
A growing body of evidence points towards epigenetic mechanisms being responsible for a wide range of biological phenomena, from the plasticity of plant growth and development to the nutritional control...
6.
Azuara D, Rodriguez-Moranta F, de Oca J, Soriano-Izquierdo A, Mora J, Guardiola J, et al.
Clin Colorectal Cancer
. 2010 Jul;
9(3):168-76.
PMID: 20643622
Background: Previous studies showed that the assessment of promoter hypermethylation of a limited number of genes in tumor biopsies may identify the majority of colorectal tumors. This study aimed to...
7.
Alazzouzi H, Suriano G, Guerra A, Plaja A, Espin E, Armengol M, et al.
J Med Genet
. 2006 Jul;
44(1):75-80.
PMID: 16825434
Background: Mdm2 is a natural inhibitor of p53 function and its overexpression impairs p53 transcriptional activity. T-->G single-nucleotide polymorphism at position 309 (SNP309) of mdm2 induces overexpression of mdm2, but...
8.
Munoz J, Vendrell E, Aiza G, Nistal M, Pestana A, Peinado M, et al.
Neuropathology
. 2006 Jun;
26(3):165-9.
PMID: 16771170
The aim of this study is to establish an estimation of the global genomic alteration in neuroblastic tumors (ganglioneuromas, ganglioneuroblastomas and neuroblastomas) and correlate them with different clinical parameters (age,...
9.
Musulen E, Moreno V, Reyes G, Sancho F, Peinado M, Esteller M, et al.
Hum Pathol
. 2004 Mar;
35(3):335-42.
PMID: 15017590
Microsatellite instability (MSI) defines a specific type of genetic instability. Although consensus diagnostic criteria for MSI definition in colorectal cancer have been established, their utility in other tumor types remain...
10.
Gemignani F, Moreno V, Landi S, Moullan N, Chabrier A, Gutierrez-Enriquez S, et al.
Oncogene
. 2003 Dec;
23(10):1954-6.
PMID: 14647431
We undertook a case-control study to examine the possible associations of the TP53 variants Arg > Pro at codon 72 and p53PIN3, a 16 bp insertion/duplication in intron 3, with...