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Manel Esteller

Explore the profile of Manel Esteller including associated specialties, affiliations and a list of published articles. Areas
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Articles 631
Citations 42006
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Recent Articles
1.
Siqueira E, Velasco C, Tarrason A, Soler M, Srinivas T, Setien F, et al.
Nucleic Acids Res . 2025 Feb; 53(4). PMID: 39970285
Rett syndrome (RTT) is a severe neurodevelopmental disorder primarily caused by loss-of-function mutations in the MECP2 gene, resulting in diverse cellular dysfunctions. Here, we investigated the role of the long...
2.
Siqueira E, Velasco C, Tarrason A, Soler M, Srinivas T, Setien F, et al.
Nucleic Acids Res . 2025 Feb; 53(4). PMID: 39921568
Rett syndrome (RTT) is a severe neurodevelopmental disorder primarily caused by loss-of-function mutations in the MECP2 gene, resulting in diverse cellular dysfunctions. Here, we investigated the role of the long...
3.
Genius P, Calle M, Rodriguez-Fernandez B, Minguillon C, Cacciaglia R, Garrido-Martin D, et al.
Alzheimers Dement . 2025 Jan; 21(2):e14490. PMID: 39868465
Introduction: Traditional multivariate methods for neuroimaging studies overlook the interdependent relationship between brain features. This study addresses this gap by analyzing relative brain volumetric patterns to capture how Alzheimer's disease...
4.
Sibai M, Cervilla S, Grases D, Musulen E, Lazcano R, Mo C, et al.
Cell Rep . 2025 Jan; 44(2):115229. PMID: 39864059
Tumors are complex ecosystems of interacting cell types. The concept of cancer hallmarks distills this complexity into underlying principles that govern tumor growth. Here, we explore the spatial distribution of...
5.
Vasileva F, Font-Llado R, Lopez-Ros V, Barretina J, Noguera-Castells A, Esteller M, et al.
Scand J Med Sci Sports . 2025 Jan; 35(1):e70012. PMID: 39757698
Physical exercise has been shown to induce epigenetic modifications with various health implications, directly affect DNA methylation (DNAm), as well as reverse the epigenetic age. Hence, we aimed to identify...
6.
Chen L, Wang X, Xie N, Zhang Z, Xu X, Xue M, et al.
Mol Oncol . 2024 Dec; 19(1):173-187. PMID: 39630602
High-order interactions associated with non-small cell lung cancer (NSCLC) survival may elucidate underlying molecular mechanisms and identify potential therapeutic targets. Our previous work has identified a three-way interaction among pack-year...
7.
Noguera-Castells A, Garcia-Prieto C, Ferrer G, Davalos V, Setien F, Genesca E, et al.
Leukemia . 2024 Nov; 39(2):512-515. PMID: 39578534
No abstract available.
8.
Perron U, Grassi E, Chatzipli A, Viviani M, Karakoc E, Trastulla L, et al.
Nat Commun . 2024 Nov; 15(1):9139. PMID: 39528460
Patient-derived xenografts (PDXs) are tumour fragments engrafted into mice for preclinical studies. PDXs offer clear advantages over simpler in vitro cancer models - such as cancer cell lines (CCLs) and...
9.
Esteller M
Br J Haematol . 2024 Nov; 206(2):785-787. PMID: 39523653
In this article, Chen et al. show that a chemical modification of transfer RNA, along its corresponding RNA modifier enzyme, is diminished in acute myeloid leukaemia. These findings further support...
10.
Gamez-Garcia A, Espinosa-Alcantud M, Bueno-Costa A, Alari-Pahissa E, Marazuela-Duque A, Thackray J, et al.
Nat Immunol . 2024 Oct; 25(12):2308-2319. PMID: 39424985
B lymphopoiesis is orchestrated by lineage-specific transcription factors. In B cell progenitors, lineage commitment is mediated by Pax5, which is commonly mutated in B cell acute lymphoblastic leukemia. Despite its...