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Miguel A Ballicora

Explore the profile of Miguel A Ballicora including associated specialties, affiliations and a list of published articles. Areas
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Articles 58
Citations 757
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Recent Articles
1.
Patel H, Martinez-Ramirez G, Dobrzynski E, Iglesias A, Liu D, Ballicora M
Protein Sci . 2023 Aug; 32(9):e4747. PMID: 37551561
ADP-glucose pyrophosphorylase is a key regulatory enzyme involved in starch and glycogen synthesis in plants and bacteria, respectively. It has been hypothesized that inter-subunit communications are important for the allosteric...
2.
Variot C, Capule D, Arolli X, Baumgartner J, Reidl C, Houseman C, et al.
Protein Sci . 2023 Jul; 32(8):e4725. PMID: 37418656
An increased understanding of how the acceptor site in Gcn5-related N-acetyltransferase (GNAT) enzymes recognizes various substrates provides important clues for GNAT functional annotation and their use as chemical tools. In...
3.
Alghamdi M, Hussien R, Zheng Y, Patel H, Asencion Diez M, Iglesias A, et al.
Protein Sci . 2022 Jun; 31(7):e4376. PMID: 35762722
The allosteric regulation of ADP-glucose pyrophosphorylase is critical for the biosynthesis of glycogen in bacteria and starch in plants. The enzyme from Agrobacterium tumefaciens is activated by fructose 6-phosphate (Fru6P)...
4.
Bhayani J, Iglesias M, Minen R, Cereijo A, Ballicora M, Iglesias A, et al.
Front Microbiol . 2022 May; 13:867384. PMID: 35572620
We explored the ability of ADP-glucose pyrophosphorylase (ADP-Glc PPase) from different bacteria to use glucosamine (GlcN) metabolites as a substrate or allosteric effectors. The enzyme from the actinobacteria exhibited marked...
5.
Minen R, Bhayani J, Hartman M, Cereijo A, Zheng Y, Ballicora M, et al.
Plant Cell Physiol . 2022 Mar; 63(5):658-670. PMID: 35243499
Sugar alcohols are major photosynthetic products in plant species from the Apiaceae and Plantaginaceae families. Mannose-6-phosphate reductase (Man6PRase) and aldose-6-phosphate reductase (Ald6PRase) are key enzymes for synthesizing mannitol and glucitol...
6.
Figueroa C, Asencion Diez M, Ballicora M, Iglesias A
Plant Mol Biol . 2022 Jan; 108(4-5):307-323. PMID: 35006475
This review outlines research performed in the last two decades on the structural, kinetic, regulatory and evolutionary aspects of ADP-glucose pyrophosphorylase, the regulatory enzyme for starch biosynthesis. ADP-glucose pyrophosphorylase (ADP-Glc...
7.
Bhayani J, Ballicora M
Biochem Biophys Res Commun . 2021 Dec; 590:1-6. PMID: 34959191
The thermal shift assay (TSA) is a powerful tool used to detect molecular interactions between proteins and ligands. Using temperature as a physical denaturant and an extrinsic fluorescent dye, the...
8.
Ferretti M, Hussien R, Ballicora M, Iglesias A, Figueroa C, Asencion Diez M
Biochimie . 2021 Sep; 192:30-37. PMID: 34560201
Until recently, the cyanobacterial phylum only included oxygenic photosynthesizer members. The discovery of Melainabacteria as a group of supposed non-photosynthetic cyanobacteria asked to revisit such scenario. From metagenomic data, we...
9.
Baumgartner J, Mohammad T, Czub M, Majorek K, Arolli X, Variot C, et al.
Front Mol Biosci . 2021 Apr; 8:646046. PMID: 33912589
Enzymes in the Gcn5-related acetyltransferase (GNAT) superfamily are widespread and critically involved in multiple cellular processes ranging from antibiotic resistance to histone modification. While acetyl transfer is the most widely...
10.
Ferrero D, Piattoni C, Asencion Diez M, Rojas B, Hartman M, Ballicora M, et al.
Front Plant Sci . 2020 Aug; 11:1058. PMID: 32754189
Starch is the dominant reserve polysaccharide accumulated in the seed of grasses (like wheat). It is the most common carbohydrate in the human diet and a material applied to the...