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Mieu M Brooks

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Articles 6
Citations 111
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Recent Articles
1.
Luo Y, Gadd M, Qie Y, Otamendi-Lopez A, Sanchez-Garavito J, Brooks M, et al.
Mol Ther Oncol . 2024 Nov; 32(4):200891. PMID: 39498357
Chimeric antigen receptor (CAR) T cell therapy has encountered limited success in solid tumors. The lack of dependable antigens and the immunosuppressive tumor microenvironment (TME) are major challenges. Within the...
2.
Norton E, Whaley L, Jones V, Brooks M, Russo M, Morderer D, et al.
Sci Adv . 2024 Aug; 10(32):eadn1607. PMID: 39110807
Glioblastoma (GBM) is the most prevalent and aggressive malignant primary brain tumor. GBM proximal to the lateral ventricles (LVs) is more aggressive, potentially because of subventricular zone contact. Despite this,...
3.
Norton E, Whaley L, Jones V, Brooks M, Russo M, Morderer D, et al.
bioRxiv . 2023 Sep; PMID: 37662251
Highlights: Periventricular GBM is more malignant and disrupts neurogenesis in a rodent model.Cell-specific proteomics elucidates tumor-promoting crosstalk between GBM and NPCs.NPCs induce upregulated CTSB expression in GBM, promoting tumor progression.GBM...
4.
Ayers J, Brooks M, Rutherford N, Howard J, Sorrentino Z, Riffe C, et al.
J Virol . 2016 Nov; 91(2). PMID: 27852849
Importance: The misfolding and accumulation of α-synuclein (αS) inclusions are found in a number of neurodegenerative disorders and is a hallmark feature of Parkinson's disease (PD) and PD-related diseases. Similar...
5.
Sacino A, Brooks M, Chakrabarty P, Saha K, Khoshbouei H, Golde T, et al.
J Neurochem . 2016 Jul; 140(4):662-678. PMID: 27424880
Progression of α-synuclein inclusion pathology may occur through cycles of release and uptake of α-synuclein aggregates, which induce additional intracellular α-synuclein inclusion pathology. This process may explain (i) the presence...
6.
Dries D, Zhu Y, Brooks M, Forero D, Adachi M, Cenik B, et al.
J Biol Chem . 2016 Mar; 291(22):11647-56. PMID: 27008863
The biological underpinnings and the pathological lesions of psychiatric disorders are centuries-old questions that have yet to be understood. Recent studies suggest that schizophrenia and related disorders likely have their...