Mieke F van Essen
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Explore the profile of Mieke F van Essen including associated specialties, affiliations and a list of published articles.
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9
Citations
63
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Recent Articles
1.
van Essen M, Peereboom E, Schlagwein N, van Gijlswijk-Janssen D, Nelemans T, Joeloemsingh J, et al.
Immunobiology
. 2023 Mar;
228(3):152364.
PMID: 36881973
Factor H is a pivotal complement regulatory protein that is preferentially produced by the liver and circulates in high concentrations in serum. There has been an increasing interest in the...
2.
Gaykema L, van Nieuwland R, Dekkers M, van Essen M, Heidt S, Zaldumbide A, et al.
Front Immunol
. 2023 Jan;
13:1058763.
PMID: 36713440
End stage renal disease is an increasing problem worldwide driven by aging of the population and increased prevalence of metabolic disorders and cardiovascular disease. Currently, kidney transplantation is the only...
3.
van Essen M, Schlagwein N, van Gijlswijk-Janssen D, Ruben J, van Kooten C
Immunobiology
. 2022 Jul;
227(4):152246.
PMID: 35843030
The complement system does not only play an important role in the defence against microorganism and pathogens, but also contributes to the regulation of innate and adaptive immunity. Especially activation...
4.
van Essen M, Schlagwein N, van den Hoven E, van Gijlswijk-Janssen D, Lubbers R, van den Bos R, et al.
Eur J Immunol
. 2022 Jan;
52(4):597-608.
PMID: 35092629
Properdin, the only known positive regulator of the complement system, stabilizes the C3 convertase, thereby increasing its half-life. In contrast to most other complement factors, properdin is mainly produced extrahepatically...
5.
Koopman J, van Essen M, Rennke H, de Vries A, van Kooten C
Front Immunol
. 2021 Mar;
11:599974.
PMID: 33643288
The membrane attack complex-also known as C5b-9-is the end-product of the classical, lectin, and alternative complement pathways. It is thought to play an important role in the pathogenesis of various...
6.
Zhang H, Prins J, Vreeken D, Florijn B, de Bruin R, van Hengel O, et al.
Innate Immun
. 2020 Nov;
27(2):118-132.
PMID: 33241976
In response to inflammatory cytokines and chemokines, monocytes differentiate into macrophages. Comprehensive analysis of gene expression regulation of neuronal guidance cue (NGC) ligands and receptors in the monocyte-to-macrophage differentiation process...
7.
van Essen M, Schlagwein N, van Gijlswijk-Janssen D, Anholts J, Eikmans M, Ruben J, et al.
J Immunol Methods
. 2020 Jan;
479:112748.
PMID: 31958452
Gene silencing using small interfering ribonucleic acids (siRNA) is a powerful method to interfere with gene expression, allowing for the functional exploration of specific genes. siRNA interference can be applied...
8.
van Essen M, Ruben J, de Vries A, van Kooten C
Nephrol Dial Transplant
. 2018 Jul;
34(5):742-750.
PMID: 30053164
As part of the innate immune system, the complement system is an important mechanism in our first line of defence, but it can also contribute to the onset of various...
9.
van Alem C, Boonstra M, Prins J, Bezhaeva T, van Essen M, Ruben J, et al.
Nephrol Dial Transplant
. 2017 Oct;
33(1):44-53.
PMID: 28992069
Background: Treatment of inflammatory kidney diseases with systemic high-dose glucocorticoids (GCs) has severe side effects. Liposomal encapsulation could facilitate local delivery of GCs to the inflamed kidney, as liposomes encapsulate...