Danielle J van Gijlswijk-Janssen
Overview
Explore the profile of Danielle J van Gijlswijk-Janssen including associated specialties, affiliations and a list of published articles.
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8
Citations
238
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Recent Articles
1.
van Essen M, Peereboom E, Schlagwein N, van Gijlswijk-Janssen D, Nelemans T, Joeloemsingh J, et al.
Immunobiology
. 2023 Mar;
228(3):152364.
PMID: 36881973
Factor H is a pivotal complement regulatory protein that is preferentially produced by the liver and circulates in high concentrations in serum. There has been an increasing interest in the...
2.
van Essen M, Schlagwein N, van Gijlswijk-Janssen D, Ruben J, van Kooten C
Immunobiology
. 2022 Jul;
227(4):152246.
PMID: 35843030
The complement system does not only play an important role in the defence against microorganism and pathogens, but also contributes to the regulation of innate and adaptive immunity. Especially activation...
3.
van Essen M, Schlagwein N, van den Hoven E, van Gijlswijk-Janssen D, Lubbers R, van den Bos R, et al.
Eur J Immunol
. 2022 Jan;
52(4):597-608.
PMID: 35092629
Properdin, the only known positive regulator of the complement system, stabilizes the C3 convertase, thereby increasing its half-life. In contrast to most other complement factors, properdin is mainly produced extrahepatically...
4.
van Essen M, Schlagwein N, van Gijlswijk-Janssen D, Anholts J, Eikmans M, Ruben J, et al.
J Immunol Methods
. 2020 Jan;
479:112748.
PMID: 31958452
Gene silencing using small interfering ribonucleic acids (siRNA) is a powerful method to interfere with gene expression, allowing for the functional exploration of specific genes. siRNA interference can be applied...
5.
van Schaarenburg R, Daha N, Schonkeren J, Levarht E, van Gijlswijk-Janssen D, Kurreeman F, et al.
Immunobiology
. 2014 Dec;
220(3):422-7.
PMID: 25454803
Introduction: C1q deficiency is a rare genetic disorder that is strongly associated with development of systemic lupus erythematosus (SLE). Several mutations in the coding regions of the C1q genes have...
6.
Oortwijn B, Roos A, Royle L, van Gijlswijk-Janssen D, Faber-Krol M, Eijgenraam J, et al.
J Am Soc Nephrol
. 2006 Oct;
17(12):3529-39.
PMID: 17050773
IgA nephropathy (IgAN) is characterized by mesangial deposition of polymeric IgA1 (pIgA1) and complement. Complement activation via mannose-binding lectin and the lectin pathway is associated with disease progression. Furthermore, recent...
7.
Roos A, Rastaldi M, Calvaresi N, Oortwijn B, Schlagwein N, van Gijlswijk-Janssen D, et al.
J Am Soc Nephrol
. 2006 May;
17(6):1724-34.
PMID: 16687629
IgA nephropathy (IgAN) is characterized by glomerular co-deposition of IgA and complement components. Earlier studies showed that IgA activates the alternative pathway of complement, whereas more recent data also indicate...
8.
Rijkelijkhuizen J, Haanstra K, Wubben J, Tons A, Roos A, van Gijlswijk-Janssen D, et al.
Transplantation
. 2003 Nov;
76(9):1359-68.
PMID: 14627916
Background: Transplantation of islets of Langerhans can restore insulin production in diabetic patients. Because of the shortage of human donor organs, transplantation of porcine islets may be an alternative solution....