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Mickael Menager

Explore the profile of Mickael Menager including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 463
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Recent Articles
1.
Perrin S, Ethel M, Bretegnier V, Goachet C, Wotawa C, Luka M, et al.
Elife . 2024 Dec; 13. PMID: 39642053
Bone regeneration is mediated by skeletal stem/progenitor cells (SSPCs) that are mainly recruited from the periosteum after bone injury. The composition of the periosteum and the steps of SSPC activation...
2.
Dieudonne Y, Lorenzetti R, Rottura J, Janowska I, Frenger Q, Jacquel L, et al.
Nat Commun . 2024 Nov; 15(1):9921. PMID: 39548093
Primary antiphospholipid syndrome (PAPS) is a life-threatening clotting disorder mediated by pathogenic autoantibodies. Here we dissect the origin of self-reactive B cells in human PAPS using peripheral blood and bone...
3.
Manfroi B, Cuc B, Sokal A, Vandenberghe A, Temmam S, Attia M, et al.
Sci Transl Med . 2024 Sep; 16(765):eadl1997. PMID: 39292802
The development of the human immune system lasts for several years after birth. The impact of this maturation phase on the quality of adaptive immunity and the acquisition of immunological...
4.
Perrin S, Ethel M, Bretegnier V, Goachet C, Wotawa C, Luka M, et al.
bioRxiv . 2024 Aug; PMID: 39211065
Bone regeneration is mediated by skeletal stem/progenitor cells (SSPCs) that are mainly recruited from the periosteum after bone injury. The composition of the periosteum and the steps of SSPC activation...
5.
Perrin S, Protic S, Bretegnier V, Laurendeau I, de Lageneste O, Panara N, et al.
Sci Transl Med . 2024 Jun; 16(753):eadj1597. PMID: 38924432
Congenital pseudarthrosis of the tibia (CPT) is a severe pathology marked by spontaneous bone fractures that fail to heal, leading to fibrous nonunion. Half of patients with CPT are affected...
6.
Kosmider O, Posseme C, Temple M, Corneau A, Carbone F, Duroyon E, et al.
Nat Commun . 2024 Jan; 15(1):910. PMID: 38291039
Acquired mutations in the UBA1 gene were recently identified in patients with severe adult-onset auto-inflammatory syndrome called VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic). However, the precise physiological and clinical...
7.
Poggi L, Chentout L, Lizot S, Boyne A, Juillerat A, Moiani A, et al.
Mol Ther Methods Clin Dev . 2023 Dec; 31:101133. PMID: 38152700
Gain-of-function mutations in the gene result in activated phosphoinositide 3-kinase δ syndrome type 1 (APDS1). This syndrome is a life-threatening combined immunodeficiency and today there are neither optimal nor long-term...
8.
Dos Santos L, Carbone F, Pacreau E, Diarra S, Luka M, Pigat N, et al.
Am J Pathol . 2023 Oct; 194(1):30-51. PMID: 37827216
Benign prostate hyperplasia (BPH) is caused by the nonmalignant enlargement of the transition zone of the prostate gland, leading to lower urinary tract symptoms. Although current medical treatments are unsatisfactory...
9.
Aquino Y, Bisiaux A, Li Z, ONeill M, Mendoza-Revilla J, Merkling S, et al.
Nature . 2023 Aug; 621(7977):120-128. PMID: 37558883
Humans display substantial interindividual clinical variability after SARS-CoV-2 infection, the genetic and immunological basis of which has begun to be deciphered. However, the extent and drivers of population differences in...
10.
Delage L, Carbone F, Riller Q, Zachayus J, Kerbellec E, Buzy A, et al.
Nat Commun . 2023 Jun; 14(1):3728. PMID: 37349339
Loss of NBEAL2 function leads to grey platelet syndrome (GPS), a bleeding disorder characterized by macro-thrombocytopenia and α-granule-deficient platelets. A proportion of patients with GPS develop autoimmunity through an unknown...