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Michiel Pegtel

Explore the profile of Michiel Pegtel including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 380
Followers 0
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Recent Articles
1.
Moldovan N, van der Pol Y, Ende T, Boers D, Verkuijlen S, Creemers A, et al.
Cell Rep Med . 2023 Dec; 5(1):101349. PMID: 38128532
The structure of cell-free DNA (cfDNA) is altered in the blood of patients with cancer. From whole-genome sequencing, we retrieve the cfDNA fragment-end composition using a new software (FrEIA [fragment...
2.
Scheepbouwer C, Hackenberg M, van Eijndhoven M, Gerber A, Pegtel M, Gomez-Martin C
Nucleic Acids Res . 2023 May; 51(W1):W372-W378. PMID: 37216599
RNA-sequencing has become one of the most used high-throughput approaches to gain knowledge about the expression of all different RNA subpopulations. However, technical artifacts, either introduced during library preparation and/or...
3.
Aparicio-Puerta E, Gomez-Martin C, Giannoukakos S, Medina J, Scheepbouwer C, Garcia-Moreno A, et al.
Nucleic Acids Res . 2022 May; 50(W1):W710-W717. PMID: 35556129
The NCBI Sequence Read Archive currently hosts microRNA sequencing data for over 800 different species, evidencing the existence of a broad taxonomic distribution in the field of small RNA research....
4.
Wachalska M, Koppers-Lalic D, van Eijndhoven M, Pegtel M, Geldof A, Lipinska A, et al.
J Circ Biomark . 2017 Sep; 5:4. PMID: 28936252
Urine exosomes (extracellular vesicles; EVs) contain (micro)RNA (miRNA) and protein biomarkers that are useful for the non-invasive diagnosis of various urological diseases. However, the urinary Tamm-Horsfall protein (THP) complex, which...
5.
Sequeiros T, Rigau M, Chiva C, Montes M, Garcia-Grau I, Garcia M, et al.
Oncotarget . 2016 Dec; 8(3):4960-4976. PMID: 27903962
Rapid and reliable diagnosis of prostate cancer (PCa) is highly desirable as current used methods lack specificity. In addition, identification of PCa biomarkers that can classify patients into high- and...
6.
Koppers-Lalic D, Hackenberg M, Menezes R, Misovic B, Wachalska M, Geldof A, et al.
Oncotarget . 2016 Mar; 7(16):22566-78. PMID: 26992225
In many cancer types, the expression and function of ~22 nucleotide-long microRNAs (miRNA) is deregulated. Mature miRNAs can be stably detected in extracellular vesicles (EVs) in biofluids, therefore they are...
7.
Aikawa E, Gardiner C, Hutcheson J, Ochiya T, Osteikoetxea X, Pegtel M, et al.
J Extracell Vesicles . 2015 Jun; 2:23070. PMID: 26082318
No abstract available.
8.
Qiu J, Cosmopoulos K, Pegtel M, Hopmans E, Murray P, Middeldorp J, et al.
PLoS Pathog . 2011 Sep; 7(8):e1002193. PMID: 21901094
We have performed the first extensive profiling of Epstein-Barr virus (EBV) miRNAs on in vivo derived normal and neoplastic infected tissues. We describe a unique pattern of viral miRNA expression...
9.
Cosmopoulos K, Pegtel M, Hawkins J, Moffett H, Novina C, Middeldorp J, et al.
J Virol . 2008 Dec; 83(5):2357-67. PMID: 19091858
Epstein-Barr Virus (EBV) establishes a long-term latent infection and is associated with a number of human malignancies that are thought to arise from deregulation of different stages of the viral...