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Michi Izawa

Explore the profile of Michi Izawa including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 25
Followers 0
Related Specialties
Endocrinology
Molecular Biology
Cell Biology
Top 10 Co-Authors
Maho Ishida
Jun Arita
Tetsuo Mitsui
Yoshihiro Kagami
Kazuyuki Takata
Yuri Yamada
Satoshi Akiba
Kaneyasu Nishimura
Junna Nakaya
Keiichi Ishihara
Published In
Endocr J
Mol Cell Endocrinol
J Steroid Biochem Mol Biol
Mol Imaging Biol
Affiliations
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Recent Articles
1.
Radioimaging Foam Cells Infiltrating Atherosclerotic Plaques in Mice Using I-labeled oxLDL as a Radiotracer
Izawa M, Kawashima H, Okuno Y, Nakaya J, Takeda M, Harada K, et al.
Mol Imaging Biol . 2024 Sep; 26(6):903-911. PMID: 39287887
Bioimaging such as magnetic resonance is used to monitor atherosclerotic plaques consisting of foam cells, which are derived from macrophages that have ingested oxidized low-density lipoprotein (oxLDL). However, the current...
2.
Rasd1 is an estrogen-responsive immediate early gene and modulates expression of late genes in rat anterior pituitary cells
Wang L, Mitsui T, Ishida M, Izawa M, Arita J
Endocr J . 2017 Aug; 64(11):1063-1071. PMID: 28835591
Dexamethasone-induced Ras-related protein 1 (Rasd1) is a member of the Ras superfamily of monomeric G proteins that have a regulatory function in signal transduction. Here we investigated the role of...
3.
Activation of G protein-coupled estrogen receptor 1 mimics, but does not mediate, the anti-proliferative action of estradiol on pituitary lactotrophs in primary culture
Mitsui T, Ishida M, Izawa M, Arita J
Endocr J . 2016 Oct; 64(1):103-115. PMID: 27760898
Estrogen binds to nuclear estrogen receptors (ERs) to modulate transcription of target genes in estrogen-responsive cells. However, recent studies have shown that estrogen also binds to cytoplasmic membrane ERs to...
4.
Differences between rat strains in the development of PRL-secreting pituitary tumors with long-term estrogen treatment: In vitro insulin-like growth factor-1-induced lactotroph proliferation and gene expression are affected in Wistar-Kyoto rats with...
Mitsui T, Ishida M, Izawa M, Arita J
Endocr J . 2013 Aug; 60(11):1251-9. PMID: 23985690
There are differences in the susceptibility of rat strains to pituitary growth and lactotroph proliferation caused by long-term treatment with estrogens. To investigate the pituitary mechanism for this strain difference...
5.
Activation of D2 dopamine receptors inhibits estrogen response element-mediated estrogen receptor transactivation in rat pituitary lactotrophs
Ishida M, Mitsui T, Izawa M, Arita J
Mol Cell Endocrinol . 2013 May; 375(1-2):58-67. PMID: 23701824
Estrogen and dopamine are major opposing regulators of the endocrine functions of pituitary lactotrophs. Dopamine inhibits estrogen-induced changes in the synthesis and secretion of prolactin, and lactotroph proliferation. We studied...
6.
Inhibition of Bcl3 gene expression mediates the anti-proliferative action of estrogen in pituitary lactotrophs in primary culture
Mitsui T, Ishida M, Izawa M, Kagami Y, Arita J
Mol Cell Endocrinol . 2011 Jul; 345(1-2):68-78. PMID: 21787835
In addition to their well-known stimulatory action, estrogens have an anti-proliferative effect. The present study was undertaken to investigate the mechanism by which 17β-estradiol (E2) inhibits insulin-like growth factor-1 (IGF-1)-induced...
7.
Absence of ligand-independent transcriptional activation of the estrogen receptor via the estrogen response element in pituitary lactotrophs in primary culture
Ishida M, Mitsui T, Izawa M, Arita J
J Steroid Biochem Mol Biol . 2009 Nov; 118(1-2):93-101. PMID: 19883758
The estrogen receptor (ER) is a ligand-activated transcription factor that enhances gene expression by binding to specific regulatory DNA sequences called estrogen response elements (EREs). In some cell lines, the...