Kaneyasu Nishimura
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Explore the profile of Kaneyasu Nishimura including associated specialties, affiliations and a list of published articles.
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47
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1019
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Recent Articles
1.
Izawa M, Kawashima H, Okuno Y, Nakaya J, Takeda M, Harada K, et al.
Mol Imaging Biol
. 2024 Sep;
26(6):903-911.
PMID: 39287887
Bioimaging such as magnetic resonance is used to monitor atherosclerotic plaques consisting of foam cells, which are derived from macrophages that have ingested oxidized low-density lipoprotein (oxLDL). However, the current...
2.
Nishimura K, Osaki H, Tezuka K, Nakashima D, Numata S, Masamizu Y
Front Neural Circuits
. 2024 Aug;
18:1453958.
PMID: 39161368
Recent advances in human pluripotent stem cell (hPSC) technologies have prompted the emergence of new research fields and applications for human neurons and brain organoids. Brain organoids have gained attention...
3.
Oonishi T, Nishimura K, Takata K, Fujimuro M, Sekine Y
Biol Pharm Bull
. 2024 Feb;
47(2):366-372.
PMID: 38325853
Neuronal regrowth after traumatic injury is strongly inhibited in the central nervous system (CNS) of adult mammals. Cell-intrinsic and extrinsic factors limit the regulation of axonal growth and regrowth of...
4.
Gima S, Oe K, Nishimura K, Ohgita T, Ito H, Kimura H, et al.
Regen Ther
. 2024 Jan;
25:229-237.
PMID: 38283940
Introduction: Cell therapeutic clinical trials using fetal mesencephalic tissue provided a proof-of-concept for regenerative therapy in patients with Parkinson's disease. Postmortem studies of patients with fetal grafts revealed that α-synuclein...
5.
Kato T, Nishimura K, Hirao M, Shimohama S, Takata K
Neuropsychopharmacol Rep
. 2023 Jun;
43(3):440-445.
PMID: 37366076
Aim: Nicotinic acetylcholine receptors (nAChRs) expressed in midbrain dopaminergic (mDA) neurons modulate mDA neuronal activity. However, their expression patterns and functional roles during mDA neuronal development remain unknown. Here, we...
6.
Nishimura K, Sif Asgrimsdottir E, Yang S, Arenas E
STAR Protoc
. 2023 Jun;
4(3):102355.
PMID: 37310863
Here, we present a protocol for the generation of functional midbrain dopaminergic (mDA) neurons from human embryonic stem cells (hESCs), which mimics the development of the human ventral midbrain. We...
7.
Inoue S, Nishimura K, Gima S, Nakano M, Takata K
Biol Pharm Bull
. 2023 Mar;
46(3):517-522.
PMID: 36858582
Parkinson's disease (PD) is an age-related disorder with selective dopaminergic (DA) neuronal degeneration in the substantia nigra pars compacta. The presence of mainly α-synuclein-composed Lewy bodies in DA neurons is...
8.
Fukuda A, Nakashima S, Oda Y, Nishimura K, Kawashima H, Kimura H, et al.
Biol Pharm Bull
. 2023 Feb;
46(2):320-333.
PMID: 36724960
Alzheimer's disease (AD) is a progressive neurodegenerative disease characterized by dementia. The most characteristic pathological changes in AD brain include extracellular amyloid-β (Aβ) accumulation and neuronal loss. Particularly, cholinergic neurons...
9.
Takata M, Nishimura K, Harada K, Iwasaki R, Ando M, Yamada S, et al.
Tissue Cell
. 2023 Jan;
81:102023.
PMID: 36709697
The extracellular accumulation of amyloid-β (Aβ) in plaques and associated neurodegeneration are the pathological hallmarks of Alzheimer's disease (AD). These plaques are surrounded by microglia-the resident tissue macrophages of the...
10.
Nishimura K, Takata K
Nihon Yakurigaku Zasshi
. 2023 Jan;
158(1):52-56.
PMID: 36596492
Neurodegenerative disorders including Alzheimer's disease (AD) and Parkinson's disease (PD) are hard to treat once they have suffered. Therefore, the establishment of new prevention and treatment methods for neurodegenerative disorders...