Michelle Michels
Overview
Explore the profile of Michelle Michels including associated specialties, affiliations and a list of published articles.
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152
Citations
3244
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Recent Articles
1.
Tadros R, Zheng S, Grace C, Jorda P, Francis C, West D, et al.
Nat Genet
. 2025 Feb;
57(3):530-538.
PMID: 39966646
Hypertrophic cardiomyopathy (HCM) is an important cause of morbidity and mortality with both monogenic and polygenic components. Here, we report results from a large genome-wide association study and multitrait analysis...
2.
Zheng S, Jurgens S, McGurk K, Xu X, Grace C, Theotokis P, et al.
Nat Genet
. 2025 Feb;
57(3):563-571.
PMID: 39966645
Hypertrophic cardiomyopathy (HCM) is an important cause of morbidity and mortality, with pathogenic variants found in about a third of cases. Large-scale genome-wide association studies (GWAS) demonstrate that common genetic...
3.
Gigli M, Stolfo D, Barbati G, Graw S, Chen S, Merlo M, et al.
JAMA Cardiol
. 2025 Feb;
PMID: 39937464
Importance: Filamin C truncating variants (FLNCtv) are a rare cause of cardiomyopathy with heterogeneous phenotypic presentations. Despite a high incidence of life-threatening ventricular arrhythmias and sudden cardiac death (SCD), reliable...
4.
Achten A, Muller S, Zwetsloot P, Michels M, van der Meer P, Nienhuis H, et al.
Expert Rev Cardiovasc Ther
. 2025 Feb;
23(1-2):1-4.
PMID: 39928028
No abstract available.
5.
Hermus M, Scharloo-Karels C, Ikram M, Andrinopoulou E, Rizopoulos D, Marck D, et al.
Eur J Intern Med
. 2025 Jan;
133:100-105.
PMID: 39884922
Importance: Optimal data availability for secondary use is crucial for continuous improvement in healthcare. At the same time, it is imperative to uphold patients' rights to be informed, to control...
6.
Butters A, Arnott C, Sweeting J, Claggett B, Cuomo A, Cuomo A, et al.
Circ Genom Precis Med
. 2025 Jan;
18(1):e004641.
PMID: 39851041
Background: Females with hypertrophic cardiomyopathy present at a more advanced stage of the disease and have a higher risk of heart failure and death. The factors behind these differences are...
7.
van der Velde N, Poleij A, Lenzen M, Budde R, Brabander T, Miedema J, et al.
Neth Heart J
. 2025 Jan;
33(2):55-64.
PMID: 39786690
Background: Cardiac sarcoidosis (CS) is associated with poor prognosis, making early diagnosis and treatment important. This study evaluated the results of a diagnostic approach in patients with known sarcoidosis and...
8.
Schoonvelde S, Alexandridis G, Price L, Schinkel A, Hirsch A, Zwetsloot P, et al.
Int J Cardiol
. 2025 Jan;
422:132951.
PMID: 39746469
Aims: (i) Investigate the prevalence of hypertrophic cardiomyopathy (HCM) in individuals with pathogenic/likely pathogenic (P/LP) gene variants detected through family cascade testing in relatives, and (ii) evaluate phenotypic progression in...
9.
Koppelaar A, Michels M, Hirsch A
Eur Heart J Cardiovasc Imaging
. 2024 Dec;
26(2):381.
PMID: 39661632
No abstract available.
10.
Meisner J, Renberg A, Smith E, Tsan Y, Elder B, Bullard A, et al.
Circulation
. 2024 Dec;
PMID: 39633578
Background: Classically, hypertrophic cardiomyopathy (HCM) has been viewed as a single-gene (monogenic) disease caused by pathogenic variants in sarcomere genes. Pathogenic sarcomere variants are individually rare and convey high risk...