Arend F L Schinkel
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Explore the profile of Arend F L Schinkel including associated specialties, affiliations and a list of published articles.
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187
Citations
2107
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Recent Articles
1.
van der Velde N, Poleij A, Lenzen M, Budde R, Brabander T, Miedema J, et al.
Neth Heart J
. 2025 Jan;
33(2):55-64.
PMID: 39786690
Background: Cardiac sarcoidosis (CS) is associated with poor prognosis, making early diagnosis and treatment important. This study evaluated the results of a diagnostic approach in patients with known sarcoidosis and...
2.
Schoonvelde S, Alexandridis G, Price L, Schinkel A, Hirsch A, Zwetsloot P, et al.
Int J Cardiol
. 2025 Jan;
422:132951.
PMID: 39746469
Aims: (i) Investigate the prevalence of hypertrophic cardiomyopathy (HCM) in individuals with pathogenic/likely pathogenic (P/LP) gene variants detected through family cascade testing in relatives, and (ii) evaluate phenotypic progression in...
3.
Schoonvelde S, Schoonvelde S, Wiethoff I, Wiethoff I, Zwetsloot P, Zwetsloot P, et al.
Eur Heart J Qual Care Clin Outcomes
. 2024 Nov;
11(2):174-185.
PMID: 39520534
Introduction: Hypertrophic cardiomyopathy (HCM) is the most prevalent inherited cardiac disease. The impact of HCM on quality of life (QoL) and societal costs remains poorly understood. This prospective multi-centre burden...
4.
Ramdat Misier N, Amesz J, Taverne Y, Nguyen H, van Schie M, Knops P, et al.
Heart Rhythm
. 2024 Jan;
21(6):819-827.
PMID: 38246568
Background: Atrial fibrillation (AF) in patients with hypertrophic obstructive cardiomyopathy (HOCM) may be caused by a primary atrial myopathy. Whether HOCM-related atrial myopathy affects mainly electrophysiological properties of the left...
5.
Amesz J, Langmuur S, Zhang L, Manintveld O, Schinkel A, de Jong P, et al.
Biomed Pharmacother
. 2023 Dec;
170:116036.
PMID: 38134635
Hypertrophic cardiomyopathy (HCM) is the most common inherited myocardial disorder of the heart, but effective treatment options remain limited. Mavacamten, a direct myosin modulator, has been presented as novel pharmacological...
6.
Kaya E, Otten M, Theuns D, Veen K, Yap S, Schinkel A, et al.
JACC Clin Electrophysiol
. 2023 May;
9(8 Pt 1):1368-1378.
PMID: 37141904
Background: Implantable cardioverter-defibrillators (ICDs) are frequently used for primary and secondary prevention in patients with cardiomyopathies due to different etiologies. However, long-term outcome studies in patients with noncompaction cardiomyopathy (NCCM)...
7.
Huurman R, Bowen D, Mutluer F, Barreto B, van Slegtenhorst M, Verhagen J, et al.
Echocardiography
. 2022 Aug;
39(9):1209-1218.
PMID: 35978457
Background: Genetic testing of relatives of hypertrophic cardiomyopathy (HCM) patients has led to a large group of genotype-positive, phenotype-negative (G+/Ph-) subjects. Prediction of progression to overt HCM in these subjects...
8.
Tukker M, Schinkel A, Dereci A, Caliskan K
Heart Fail Rev
. 2022 Jun;
28(1):241-248.
PMID: 35689132
A subgroup of patients with noncompaction cardiomyopathy (NCCM) is at increased risk of ventricular arrhythmias and sudden cardiac death (SCD). In selected patients with NCCM, implantable cardioverter-defibrillator (ICD) therapy could...
9.
Huurman R, van der Velde N, Schinkel A, Hassing H, Budde R, van Slegtenhorst M, et al.
Eur Heart J Cardiovasc Imaging
. 2022 Jun;
23(9):1144-1154.
PMID: 35670722
Aims: Genetic testing in relatives of hypertrophic cardiomyopathy (HCM) patients leads to early identification of pathogenic DNA variant carriers (G+), before the onset of left ventricular hypertrophy. Routine phenotyping consists...
10.
Strachinaru M, Huurman R, Bowen D, Schinkel A, Hirsch A, Michels M
J Am Soc Echocardiogr
. 2022 Apr;
35(8):846-856.e2.
PMID: 35489541
Background: The early diastolic paradoxical midventricular flow is suggestive of apical aneurysm (AA) formation in hypertrophic cardiomyopathy (HCM). We aimed to determine whether early diastolic paradoxical midventricular flow may be...