Michelle Goritzka
Overview
Explore the profile of Michelle Goritzka including associated specialties, affiliations and a list of published articles.
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8
Citations
397
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0
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Recent Articles
1.
Fritzsching B, Hagner M, Dai L, Christochowitz S, Agrawal R, van Bodegom C, et al.
J Allergy Clin Immunol
. 2016 Nov;
140(1):190-203.e5.
PMID: 27865862
Background: Type 2 airway inflammation plays a central role in the pathogenesis of allergen-induced asthma, but the underlying mechanisms remain poorly understood. Recently, we demonstrated that reduced mucociliary clearance, a...
2.
Makris S, Bajorek M, Culley F, Goritzka M, Johansson C
J Innate Immun
. 2016 Jul;
8(5):452-63.
PMID: 27423203
Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infections. Immunity to RSV is initiated upon detection of the virus by pattern recognition receptors, such as RIG-I-like...
3.
Goritzka M, Pereira C, Makris S, Durant L, Johansson C
Sci Rep
. 2015 Dec;
5:18533.
PMID: 26688048
Pattern recognition receptors (PRRs) and cytokine receptors are key players in the initiation of immune responses to infection. PRRs detecting viral RNA, such as toll like receptor (TLR)-3, -7/8, and...
4.
Goritzka M, Makris S, Kausar F, Durant L, Pereira C, Kumagai Y, et al.
J Exp Med
. 2015 Apr;
212(5):699-714.
PMID: 25897172
Type I interferons (IFNs) are important for host defense from viral infections, acting to restrict viral production in infected cells and to promote antiviral immune responses. However, the type I...
5.
Durant L, Pereira C, Boakye A, Makris S, Kausar F, Goritzka M, et al.
Eur J Immunol
. 2014 Apr;
44(8):2340-8.
PMID: 24777856
During respiratory syncytial virus (RSV) infection CD8(+) T cells both assist in viral clearance and contribute to immunopathology. CD8(+) T cells recognize viral peptides presented by dendritic cells (DCs), which...
6.
Goritzka M, Durant L, Pereira C, Salek-Ardakani S, Openshaw P, Johansson C
J Virol
. 2014 Mar;
88(11):6128-36.
PMID: 24648449
Unlabelled: Type I interferons (IFNs) are produced early upon virus infection and signal through the alpha/beta interferon (IFN-α/β) receptor (IFNAR) to induce genes that encode proteins important for limiting viral...
7.
Tregoning J, Wang B, McDonald J, Yamaguchi Y, Harker J, Goritzka M, et al.
Proc Natl Acad Sci U S A
. 2013 Mar;
110(14):5576-81.
PMID: 23509276
Respiratory syncytial virus (RSV) infects most children in the first year of life and is a major single cause of hospitalization in infants and young children. There is no effective...
8.
Hammer E, Goritzka M, Ameling S, Darm K, Steil L, Klingel K, et al.
J Proteome Res
. 2011 Mar;
10(5):2161-71.
PMID: 21417265
Dilated cardiomyopathy (DCM) is characterized by contractile dysfunction leading to heart failure. The molecular changes in the human heart associated with this disease have so far mostly been addressed at...