Michele P Kelly
Overview
Explore the profile of Michele P Kelly including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
10
Citations
327
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Kelly M, Logue S, Brennan J, Day J, Lakkaraju S, Jiang L, et al.
Proc Natl Acad Sci U S A
. 2010 Apr;
107(18):8457-62.
PMID: 20404172
Phosphodiesterase 11A (PDE11A) is the most recently identified family of phosphodiesterases (PDEs), the only known enzymes to break down cyclic nucleotides. The tissue expression profile of this dual specificity PDE...
2.
Kelly M, Brandon N
Prog Brain Res
. 2010 Mar;
179:67-73.
PMID: 20302819
Phosphodiesterases (PDEs) are the only known enzymes to degrade cAMP and cGMP, intracellular signaling molecules key to numerous cellular functions. There are 11 PDE families identified to date, and each...
3.
Grauer S, Pulito V, Navarra R, Kelly M, Kelley C, Graf R, et al.
J Pharmacol Exp Ther
. 2009 Aug;
331(2):574-90.
PMID: 19661377
Following several recent reports that suggest that dual cAMP and cGMP phosphodiesterase 10A (PDE10A) inhibitors may present a novel mechanism to treat positive symptoms of schizophrenia, we sought to extend...
4.
Kelly M, Logue S, Dwyer J, Beyer C, Majchrowski H, Cai Z, et al.
Pharmacol Biochem Behav
. 2009 Mar;
92(4):649-54.
PMID: 19303035
One of the few preclinical models used to identify mood stabilizers is an assay in which amphetamine-induced hyperactivity (AMPH) is potentiated by the benzodiazepine chlordiazepoxide (CDP), an effect purportedly blocked...
5.
Favilla C, Abel T, Kelly M
J Neurosci
. 2008 Dec;
28(51):13952-6.
PMID: 19091983
Current research in the field of anxiety disorders is largely receptor-centric, leaving intracellular pathways largely unexplored. Galphas, the G-protein which stimulates adenylyl cyclase and L-type voltage-gated calcium channels, may be...
6.
Kelly M, Cheung Y, Favilla C, Siegel S, Kanes S, Houslay M, et al.
Learn Mem
. 2008 Jan;
15(2):75-83.
PMID: 18230676
Memory formation requires cAMP signaling; thus, this cascade has been of great interest in the search for cognitive enhancers. Given that medications are administered long-term, we determined the effects of...
7.
Bourtchouladze R, Patterson S, Kelly M, Kreibich A, Kandel E, Abel T
Learn Mem
. 2006 Dec;
13(6):745-52.
PMID: 17142304
The cAMP/PKA pathway plays a critical role in learning and memory systems in animals ranging from mice to Drosophila to Aplysia. Studies of olfactory learning in Drosophila suggest that altered...
8.
Kelly M, Isiegas C, Cheung Y, Tokarczyk J, Yang X, Esposito M, et al.
Neuropsychopharmacology
. 2006 Jun;
32(3):577-88.
PMID: 16738544
Sensorimotor gating, the ability to automatically filter sensory information, is deficient in a number of psychiatric disorders, yet little is known of the biochemical mechanisms underlying this critical neural process....
9.
Gould T, Bizily S, Tokarczyk J, Kelly M, Siegel S, Kanes S, et al.
Neuropsychopharmacology
. 2003 Dec;
29(3):494-501.
PMID: 14694347
Schizophrenia is a complex disorder characterized by wide-ranging cognitive impairments, including deficits in learning as well as sensory gating. The causes of schizophrenia are unknown, but alterations in intracellular G-protein...
10.
Kelly M, Deadwyler S
J Neurosci
. 2003 Jul;
23(16):6443-51.
PMID: 12878684
Previously, we demonstrated that initial acquisition of a lever-press task resulted in higher levels of activity-regulated cytoskeleton-associated protein (Arc) mRNA induction than did overtrained performance (Kelly and Deadwyler, 2002). The...