Michele H Metzgar
Overview
Explore the profile of Michele H Metzgar including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
8
Citations
140
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hondowicz B, Batheja A, Metzgar M, Caton A, Erikson J
J Autoimmun
. 2009 Dec;
34(4):460-8.
PMID: 20022728
T regulatory cells are critical for the prevention of autoimmunity. Specifically, Treg cells can control anti-chromatin antibody production in vivo, and this correlates with decreased ICOS expression on CD4(+) T...
2.
Hondowicz B, Batheja A, Metzgar M, Pagan A, Perng O, Willms S, et al.
Eur J Immunol
. 2009 Aug;
39(9):2377-82.
PMID: 19662636
T-cell recognition of peptide/MHC complexes is flexible and can lead to differential activation, but how interactions with agonist (full activation) or partial agonist (suboptimal activation) peptides can shape immune responses...
3.
Cozma D, Yu D, Hodawadekar S, Azvolinsky A, Grande S, Tobias J, et al.
J Clin Invest
. 2007 Aug;
117(9):2602-10.
PMID: 17717600
The presumed involvement of paired box gene 5 (PAX5) in B-lymphomagenesis is based largely on the discovery of Pax5-specific translocations and somatic hypermutations in non-Hodgkin lymphomas. Yet mechanistically, the contribution...
4.
Hondowicz B, Alexander S, Quinn 3rd W, Pagan A, Metzgar M, Cancro M, et al.
Int Immunol
. 2007 Mar;
19(4):465-75.
PMID: 17369193
B lymphocyte stimulator (BLyS), also known as B cell-activating factor, is a key positive regulator of B cell homeostasis, and elevated levels of BLyS have been observed in systemic lupus...
5.
Fields M, Metzgar M, Hondowicz B, Kang S, Alexander S, Hazard K, et al.
J Immunol
. 2006 May;
176(11):6491-502.
PMID: 16709806
Autoreactive B cells may become activated in a T-independent manner via synergistic engagement of the BCR and TLRs. Using the VH3H9 Ig H chain transgene to track anti-chromatin B cells,...
6.
Fields M, Hondowicz B, Metzgar M, Nish S, Wharton G, Picca C, et al.
J Immunol
. 2005 Sep;
175(7):4255-64.
PMID: 16177065
To investigate the mechanism by which T regulatory (Treg) cells may control the early onset of autoimmunity, we have used an adoptive transfer model to track Treg, Th, and anti-chromatin...
7.
Fields M, Nish S, Hondowicz B, Metzgar M, Wharton G, Caton A, et al.
J Immunol
. 2005 Jun;
175(1):104-11.
PMID: 15972636
Circulating autoantibodies against dsDNA and chromatin are a characteristic of systemic lupus erythematosus in humans and many mouse models of this disease. B cells expressing these autoantibodies are normally regulated...
8.
Fields M, Hondowicz B, Wharton G, Adair B, Metzgar M, Alexander S, et al.
Immunol Rev
. 2005 Mar;
204:165-83.
PMID: 15790358
Anti-double-stranded DNA (anti-dsDNA) B cells are regulated in non-autoimmune mice. While some are deleted or undergo receptor editing, a population of anti-dsDNA (VH3H9/V lambda 1) B cells that emigrate into...