Michel Hamon
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Explore the profile of Michel Hamon including associated specialties, affiliations and a list of published articles.
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Articles
169
Citations
3804
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Recent Articles
1.
Hamon M, Zimmer L
Therapie
. 2020 Dec;
76(2):63-66.
PMID: 33358365
For this issue, Luc Zimmer, professor of pharmacology and chair of the Neuropsychopharmacology Committee of the French Society of Pharmacology and Therapeutics, talked with Michel Hamon, honorary director of research...
2.
Vidal B, Droguerre M, Valdebenito M, Zimmer L, Hamon M, Mouthon F, et al.
Front Neurosci
. 2020 Sep;
14:835.
PMID: 32903470
Donepezil is a potent acetylcholinesterase inhibitor, largely used worldwide to alleviate cognitive symptoms in Alzheimer's disease (AD). Beyond the widely described neuronal impact of donepezil, it was recently shown that...
3.
Droguerre M, Duchene A, Picoli C, Portal B, Lejards C, Guiard B, et al.
Front Neurosci
. 2020 Jul;
14:563.
PMID: 32612499
Donepezil (DPZ) is an acetylcholinesterase inhibitor used in Alzheimer's disease to restore cognitive functions but is endowed with limited efficacy. Recent studies pointed out the implication of astroglial networks in...
4.
Martin V, Mathieu L, Diaz J, Salman H, Alterio J, Chevarin C, et al.
J Psychiatry Neurosci
. 2020 May;
45(5):344-355.
PMID: 32459080
Background: Altered function of serotonin receptor 1A (5-HT1AR) has been consistently implicated in anxiety, major depressive disorder and resistance to antidepressants. Mechanisms by which the function of 5-HT1AR (expressed as...
5.
Droguerre M, Tsurugizawa T, Duchene A, Portal B, Guiard B, Deglon N, et al.
Sci Rep
. 2019 Dec;
9(1):18292.
PMID: 31797899
Astrocytes are glial cells organized in dynamic and structured networks in the brain. These plastic networks, involving key proteins such as connexin 43 (Cx43), are engaged in fine neuronal tuning...
6.
Feng J, Lepetre-Mouelhi S, Gautier A, Mura S, Cailleau C, Coudore F, et al.
Sci Adv
. 2019 Feb;
5(2):eaau5148.
PMID: 30788432
The clinical use of endogenous neuropeptides has historically been limited due to pharmacokinetic issues, including plasma stability and blood-brain barrier permeability. In this study, we show that the rapidly metabolized...
7.
MDahoma S, Poitevin M, Dabala E, Payan H, Gabriel C, Mocaer E, et al.
Front Pharmacol
. 2018 Jun;
9:587.
PMID: 29930510
Previous data showed that neuropathic pain induced by mechanical lesion of peripheral nerves has specific characteristics and responds differently to alleviating drugs at cephalic versus extracephalic level. This is especially...
8.
Chazalon M, Dumas S, Bernard J, Sahly I, Tronche F, de Kerchove dExaerde A, et al.
Neuropharmacology
. 2018 Jun;
138:315-330.
PMID: 29908240
Serotonin (5-HT) neurons are involved in wake promotion and exert a strong inhibitory influence on rapid eye movement (REM) sleep. Such effects have been ascribed, at least in part to...
9.
Meunier A, Latremoliere A, Dominguez E, Mauborgne A, Philippe S, Hamon M, et al.
Mol Ther
. 2017 Feb;
15(4):687-697.
PMID: 28192702
Neuropathic pain developing after peripheral nerve injury is associated with altered neuronal and glial cell functions in the spinal cord. Activated glia produces algogenic mediators, exacerbating pain. Among the different...
10.
Gautier A, El Ouaraki H, Bazin N, Salam S, Vodjdani G, Bourgoin S, et al.
Exp Neurol
. 2016 Dec;
288:11-24.
PMID: 27983993
Although it is well established that bulbo-spinal serotonergic projections contribute to pain control mechanisms, whether they exert anti- or pro-nociceptive modulations is still a matter of debate. In order to...