Michel Dreano
Overview
Explore the profile of Michel Dreano including associated specialties, affiliations and a list of published articles.
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19
Citations
458
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Recent Articles
1.
Xu G, Lo Y, Li Q, Napolitano G, Wu X, Jiang X, et al.
Nature
. 2011 Mar;
472(7343):325-30.
PMID: 21423167
Inhibitor of κB (IκB) kinase (IKK) phosphorylates IκB proteins, leading to their degradation and the liberation of nuclear factor κB for gene transcription. Here we report the crystal structure of...
2.
Jordheim L, Plesa A, Dreano M, Cros-Perrial E, Keime C, Herveau S, et al.
Cancer Chemother Pharmacol
. 2010 Sep;
68(1):97-105.
PMID: 20844879
Purpose: The need for new treatment options for acute myeloid leukemia (AML) is increasing. AS602868 is a novel investigational drug with reported activity on AML cells. Methods: We studied gene...
3.
Sulpice T, Prunet-Marcassus B, Molveaux C, Cani P, Vitte P, Graber P, et al.
Endocrinology
. 2009 Jul;
150(10):4493-501.
PMID: 19608652
Adiponectin increases glucose transport, reduces inflammation, and controls vascular functions. Hence, we propose that treatment with a recombinant globular domain of adiponectin (rgAd110-244) has significant therapeutic potential to treat insulin...
4.
Lounnas N, Frelin C, Gonthier N, Colosetti P, Sirvent A, Cassuto J, et al.
Int J Cancer
. 2009 Apr;
125(2):308-17.
PMID: 19378338
The Bcr-Abl inhibitor imatinib is the current first-line therapy for all newly diagnosed chronic myeloid leukemia (CML). Nevertheless, resistance to imatinib emerges as CML progresses to an acute deadly phase...
5.
Tiberio G, Tiberio L, Benetti A, Cervi E, Montani N, Dreano M, et al.
Cytokine
. 2008 May;
42(3):372-8.
PMID: 18455423
Major hepatic resection in cirrhotic patients is associated with impaired liver regeneration and failure, leading to high peri-operative mortality. In this work, the causes of defective regeneration in cirrhotic liver...
6.
Callizot N, Andriambeloson E, Glass J, Revel M, Ferro P, Cirillo R, et al.
Cancer Chemother Pharmacol
. 2008 Feb;
62(6):995-1007.
PMID: 18270703
Purpose: This study was conducted to investigate the potential neuroprotective effect of IL-6 on chemotherapy induced neuropathy (CIN). IL-6 was compared to four-methylcatechol (4-MC)-a known inducer of NGF secretion previously...
7.
Sors A, Jean-Louis F, Begue E, Parmentier L, Dubertret L, Dreano M, et al.
Clin Cancer Res
. 2008 Feb;
14(3):901-11.
PMID: 18245554
Purpose: A key molecular feature of cutaneous T-cell lymphomas (CTCL) is the constitutive activation of the nuclear factor-kappaB (NF-kappaB) transcription factor. We investigated in vitro the effects on CTCL survival...
8.
Romagnoli M, Desplanques G, Maiga S, LeGouill S, Dreano M, Bataille R, et al.
Clin Cancer Res
. 2007 Oct;
13(20):6010-8.
PMID: 17947462
Purpose: Intrinsic activation of nuclear factor kappaB (NF-kappaB) characterizes various hematologic malignancies. In this study, we specifically address the role of NF-kappaB blockade in mediated antimyeloma activity using the IkappaB...
9.
Tiberio G, Tiberio L, Benetti A, Cervi E, Pandolfo G, Dreano M, et al.
Hepatogastroenterology
. 2007 Jun;
54(75):878-83.
PMID: 17591083
Background/aims: In the liver IL-6 displays growth-inducing and pro-survival activities. We studied the pro-proliferative and protective mechanisms of IL-6 treatment in a model of liver cirrhosis in wild type rat,...
10.
Jourdan M, Moreaux J, De Vos J, Hose D, Mahtouk K, Abouladze M, et al.
Br J Haematol
. 2007 Jun;
138(2):160-8.
PMID: 17542984
The pathophysiologic basis for multiple myeloma (MM) has been attributed to the dysregulation of various paracrine or autocrine growth factor loops and to perturbations in several signal transduction pathways including...