Michal Laniado-Schwartzman
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Explore the profile of Michal Laniado-Schwartzman including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Laffer C, Gainer J, Waterman M, Capdevila J, Laniado-Schwartzman M, Nasjletti A, et al.
Hypertension
. 2008 Jan;
51(3):767-72.
PMID: 18227405
A role for a deficit in transport actions of 20-hydroxyeicosatetraenoic acid (20-HETE) in hypertension is supported by the following: (1) diminished renal 20-HETE in Dahl-S rats; (2) altered salt- and...
12.
Ishizuka T, Cheng J, Singh H, Vitto M, Manthati V, Falck J, et al.
J Pharmacol Exp Ther
. 2007 Oct;
324(1):103-10.
PMID: 17947496
Endothelial dysfunction is associated with endothelial cell activation, i.e., up-regulation of surface cell adhesion molecules and the release of proinflammatory cytokines. 20-Hydroxyeicosatetraenoic acid (HETE), a major vasoactive eicosanoid in the...
13.
Biteman B, Hassan I, Walker E, Leedom A, Dunn M, Seta F, et al.
FASEB J
. 2007 Mar;
21(9):2257-66.
PMID: 17384141
In the immune-privileged cornea, epithelial wounds heal rapidly with almost no scarring and, unlike in most other tissues, acute inflammation in the absence of infection is beneficial to healing. Molecular...
14.
Seta F, Bellner L, Rezzani R, Regan R, Dunn M, Abraham N, et al.
Am J Pathol
. 2006 Oct;
169(5):1612-23.
PMID: 17071585
Heme oxygenase (HO) represents an intrinsic anti-inflammatory system based on its ability to regulate leukocyte function and inhibit expression of proinflammatory cytokines. This anti-inflammatory function is linked to the inducible...
15.
Wang J, Singh H, Zhang F, Ishizuka T, Deng H, Kemp R, et al.
Circ Res
. 2006 Mar;
98(7):962-9.
PMID: 16543501
Vascular cytochrome P450 (CYP) 4A enzymes catalyze the synthesis of 20-hydroxyeicosatetraenoic acid (20-HETE), an eicosanoid which participates in the regulation of vascular tone by sensitizing the smooth muscle cells to...
16.
Seki T, Wang M, Miyata N, Laniado-Schwartzman M
Biol Pharm Bull
. 2005 Sep;
28(9):1651-4.
PMID: 16141533
We examined the effect of N-hydroxy-N'-(4-butyl-2-methylphenyl)-formamidine) (HET0016), an inhibitor of 20-hydroxy-5,8,11,14-eicosatetraenoic acid (20-HETE) synthesis on the omega-hydroxylation and epoxidation of arachidonic acid (AA) catalyzed by recombinant cytochrome P450 4A1 (CYP4A1),...
17.
Mezentsev A, Mastyugin V, Seta F, Ashkar S, Kemp R, Reddy D, et al.
J Pharmacol Exp Ther
. 2005 Jul;
315(1):42-50.
PMID: 16009741
Injury to the ocular surface induces the production of the corneal epithelial-derived 12-hydroxyeicosatetrienoic acid (12-HETrE), which exhibits stereospecific potent inflammatory and angiogenic properties and is formed by a cytochrome P450...
18.
Zhang F, Deng H, Kemp R, Singh H, Gopal V, Falck J, et al.
Hypertension
. 2004 Dec;
45(1):103-8.
PMID: 15569854
We compared renal interlobar arteries of spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) in terms of cytochrome P450 (CYP) 4A and CYP2E1 protein expression; levels of 20-HETE, 19-HETE, and...
19.
Wang J, Zhang F, Jiang M, Wang M, Zand B, Abraham N, et al.
J Pharmacol Exp Ther
. 2004 Jul;
311(3):913-20.
PMID: 15269250
20-hydroxyeicosatetraenoic acid (20-HETE), a CYP4A-derived arachidonic acid metabolite, is a potent vasoconstrictor and a modulator of vascular reactivity. We have shown that CYP4A1 and CYP4A2 are the major CYP4A isoforms...
20.
Vascular CO counterbalances the sensitizing influence of 20-HETE on agonist-induced vasoconstriction
Kaide J, Zhang F, Wei Y, Wang W, Gopal V, Falck J, et al.
Hypertension
. 2004 Jul;
44(2):210-6.
PMID: 15226275
We examined the influence of interactions between CO and 20-hydroxyeicosatetraenoic acid (20-HETE) on vascular reactivity to phenylephrine and vasopressin. Renal interlobar arteries incubated in Krebs buffer released CO at a...