Michal Chodynski
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Explore the profile of Michal Chodynski including associated specialties, affiliations and a list of published articles.
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20
Citations
162
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Recent Articles
1.
Piatek K, Kutner A, Cacsire Castillo-Tong D, Manhardt T, Kupper N, Nowak U, et al.
Int J Mol Sci
. 2022 Jan;
23(1).
PMID: 35008598
Background: Ovarian cancer (OC) is one of the most lethal cancers in women. The active form of vitamin D, 1,25-dihydroxyvitamin D (1,25D, calcitriol) has anticancer activity in several cancers, including...
2.
Vitamin D Compounds PRI-2191 and PRI-2205 Enhance Anastrozole Activity in Human Breast Cancer Models
Filip-Psurska B, Psurski M, Anisiewicz A, Libako P, Zbrojewicz E, Maciejewska M, et al.
Int J Mol Sci
. 2021 Apr;
22(5).
PMID: 33803480
1,25-Dihydroxycholecalciferol, the hormonally active vitamin D metabolite, is known to exhibit therapeutic effects against breast cancer, mainly by lowering the expression of estrogen receptors and aromatase activity. Previously, the safety...
3.
Maj E, Maj B, Bobak K, Gos M, Chodynski M, Kutner A, et al.
Int J Mol Sci
. 2021 Mar;
22(5).
PMID: 33652978
Plant polyphenols and vitamins D exhibit chemopreventive and therapeutic anticancer effects. We first evaluated the biological effects of the plant polyphenol resveratrol (RESV) and vitamin D active metabolite PRI-2191 on...
4.
Piotrowska A, Wierzbicka J, Kwiatkowska K, Chodynski M, Kutner A, Zmijewski M
Eur J Pharmacol
. 2020 May;
881:173170.
PMID: 32445704
Vitamin D compounds are versatile molecules widely considered as promising agents in cancer prevention and treatment, including melanoma. Previously we investigated series of double point modified vitamin D analogs as...
5.
Milczarek M, Chodynski M, Pietraszek A, Stachowicz-Suhs M, Yasuda K, Sakaki T, et al.
Int J Mol Sci
. 2020 Jan;
21(2).
PMID: 31963716
Experimental data indicate that low-calcemic vitamin D derivatives (VDDs) exhibit anticancer properties, both and . In our search for a vitamin D analog as potential anticancer agent, we investigated the...
6.
Berkowska K, Corcoran A, Grudzien M, Jakuszak A, Chodynski M, Kutner A, et al.
Int J Mol Sci
. 2019 Aug;
20(17).
PMID: 31455010
1,25-dihydroxyvitamin D (1,25D3) is implicated in many cellular functions, including cell proliferation and differentiation, thus exerting potential antitumor effects. A major limitation for therapeutic use of 1,25D3 are potent calcemic...
7.
Maj E, Trynda J, Maj B, Gebura K, Bogunia-Kubik K, Chodynski M, et al.
J Steroid Biochem Mol Biol
. 2019 Jul;
193:105431.
PMID: 31326626
Vitamin D reveals antiproliferative activity against many types of cancer cells. Calcitriol (1,25D3), the most active form of vitamin D3, acts mainly through the vitamin D receptor, regulating the expression...
8.
Dams I, Bialonska A, Cmoch P, Krupa M, Pietraszek A, Ostaszewska A, et al.
Molecules
. 2017 Aug;
22(8).
PMID: 28809817
Two unknown impurities were observed during the process development for multigram-scale synthesis of eplerenone (Inspra). The new process-related impurities were identified and fully characterized as the corresponding (7β,11α,17α)-11-hydroxy- and (7α,11β,17α)-9,11-dichloroeplerenone...
9.
Krupa M, Chodynski M, Ostaszewska A, Cmoch P, Dams I
Molecules
. 2017 Feb;
22(2).
PMID: 28146132
Tafluprost (AFP-168, 5) is a unique 15-deoxy-15,15-difluoro-16-phenoxy prostaglandin F2α (PGF2α) analog used as an efficacious ocular hypotensive agent in the treatment of glaucoma and ocular hypertension, as monotherapy, or as...
10.
Trynda J, Turlej E, Milczarek M, Pietraszek A, Chodynski M, Kutner A, et al.
Int J Mol Sci
. 2015 Oct;
16(10):24873-94.
PMID: 26492238
Analogs of 1,25-dihydroxyergocalciferol, modified in the side-chain and in the A-ring, were tested for their antiproliferative activity against a series of human cancer cell lines in vitro and in vivo...