Michal Caspi
Overview
Explore the profile of Michal Caspi including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
424
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Recent Articles
1.
Zelikson N, Ben S, Caspi M, Tarabe R, Shaleve Y, Pri-Paz Basson Y, et al.
Cell Commun Signal
. 2024 Apr;
22(1):229.
PMID: 38622714
The β-catenin dependent canonical Wnt signaling pathway plays a crucial role in maintaining normal homeostasis. However, when dysregulated, Wnt signaling is closely associated with various pathological conditions, including inflammation and...
2.
Wittenstein A, Caspi M, Rippin I, Elroy-Stein O, Eldar-Finkelman H, Thoms S, et al.
PLoS Biol
. 2024 Feb;
22(2):e3002524.
PMID: 38354369
[This corrects the article DOI: 10.1371/journal.pbio.3002355.].
3.
Wittenstein A, Caspi M, Rippin I, Elroy-Stein O, Eldar-Finkelman H, Thoms S, et al.
PLoS Biol
. 2023 Nov;
21(11):e3002355.
PMID: 37943958
The introduction of premature termination codons (PTCs), as a result of splicing defects, insertions, deletions, or point mutations (also termed nonsense mutations), lead to numerous genetic diseases, ranging from rare...
4.
Armoza-Eilat S, Malis Y, Caspi M, Tarabe R, Shomron O, Hirschberg K, et al.
J Mol Biol
. 2023 Jun;
435(15):168171.
PMID: 37285900
Carboxypeptidase E (CPE), an essential enzyme in the biosynthetic production line of most peptide hormones and neuropeptides, is predominantly expressed in endocrine tissues and in the nervous system. CPE is...
5.
Siman-Tov R, Shalabi R, Shlomai A, Goldberg E, Essa W, Shusterman E, et al.
Int J Mol Sci
. 2022 Nov;
23(22).
PMID: 36430724
Coronavirus disease-19 (COVID-19) patients are prone to thrombotic complications that may increase morbidity and mortality. These complications are thought to be driven by endothelial activation and tissue damage promoted by...
6.
Evron T, Caspi M, Kazelnik M, Shor-Nareznoy Y, Armoza-Eilat S, Kariv R, et al.
Oncogenesis
. 2021 Sep;
10(9):63.
PMID: 34552058
The Wnt signaling pathways play fundamental roles during both development and adult homeostasis. Aberrant activation of the canonical Wnt signal transduction pathway is involved in many diseases including cancer, and...
7.
Siman-Tov R, Zelikson N, Caspi M, Levi Y, Perry C, Khair F, et al.
Arterioscler Thromb Vasc Biol
. 2021 Feb;
41(5):e243-e264.
PMID: 33626913
[Figure: see text].
8.
Caspi M, Wittenstein A, Kazelnik M, Shor-Nareznoy Y, Rosin-Arbesfeld R
Adv Drug Deliv Rev
. 2020 Dec;
169:118-136.
PMID: 33346022
The canonical Wnt pathway is one of the key cellular signaling cascades that regulates, via the transcriptional co-activator β-catenin, numerous embryogenic developmental processes, as well as tissue homeostasis. It is...
9.
Nadar-Ponniah P, Taiber S, Caspi M, Koffler-Brill T, Dror A, Siman-Tov R, et al.
Front Cell Dev Biol
. 2020 Aug;
8:615.
PMID: 32766247
Striatin, a subunit of the serine/threonine phosphatase PP2A, is a core member of the conserved striatin-interacting phosphatase and kinase (STRIPAK) complexes. The protein is expressed in the cell junctions between...
10.
Wittenstein A, Caspi M, David Y, Shorer Y, Nadar-Ponniah P, Rosin-Arbesfeld R
J Mol Med (Berl)
. 2019 Dec;
97(12):1695-1710.
PMID: 31786671
Of all genetic mutations causing human disease, premature termination codons (PTCs) that result from splicing defaults, insertions, deletions, and point mutations comprise around 30%. From these mutations, around 11% are...