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Michael W Y Chan

Explore the profile of Michael W Y Chan including associated specialties, affiliations and a list of published articles. Areas
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Articles 115
Citations 2197
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Recent Articles
1.
Yang S, Jhang J, Huang W, Tsai L, Tsai M, Chan C, et al.
Mol Carcinog . 2024 Dec; 64(3):440-449. PMID: 39620386
Ovarian cancer is one of the most common gynecologic cancers. In the quest for effective anti-cancer agents, this study explores the effects of wogonin, a naturally occurring flavonoid, on the...
2.
Chen L, Yang S, Chou J, Chou H, Yeh C, Chiu C, et al.
Mol Carcinog . 2024 Nov; 64(2):290-304. PMID: 39540800
The role of TGF-β signaling in the epigenetic modifications involved in ovarian cancer is not fully understood. This study investigated the relationship between TGF-β signaling, epigenetic modifications, and cellular behaviors...
3.
Yu C, Lin H, Chan M, Wu S, Chiou W, Lee M, et al.
Cancer Cell Int . 2024 Nov; 24(1):373. PMID: 39529064
Purpose: We tested whether the PARP inhibitor, Olaparib, can effectively enhance radiosensitivity while inhibiting OSCC growth and metastasis in vitro and in vivo. Patient samples were used for survival validation....
4.
Hung S, Lee M, Chiou W, Liu D, Yu C, Chen L, et al.
Tzu Chi Med J . 2024 Oct; 36(4):396-406. PMID: 39421493
Radiotherapy (RT) is one of the primary treatment modalities in managing cancer patients. Recently, combined RT and immunotherapy (IT) (i.e., radio-IT [RIT]) have been aggressively investigated in managing cancer patients....
5.
Low J, Chan M, Shen C, Wei K
Mol Biol Rep . 2024 Sep; 51(1):959. PMID: 39230620
Cancer remains a global health burden, shaped by both genetic mutations and epigenetic dysregulation. Epigenetic alteration plays a pivotal role in tumorigenesis, immune response modulation, and the emergence of treatment...
6.
Liu X, Chen B, Xie F, Wong K, Cheung A, Zhang J, et al.
Cancer Res . 2024 Jul; 84(21):3574-3588. PMID: 39047223
The Hippo-YAP1 pathway is an evolutionally conserved signaling cascade that controls organ size and tissue regeneration. Dysregulation of Hippo-YAP1 signaling promotes initiation and progression of several types of cancer, including...
7.
Banerjee P, Dey G, Maity J, Stewart K, Sharma R, Chan M, et al.
Ecol Evol . 2024 Apr; 14(4):e11268. PMID: 38646006
The cryptic invasion of golden apple snails (. ) in Taiwan has caused significant ecological and economical damage over the last few decades, however, their management remains difficult due to...
8.
Jiang Y, Liu Y, Wei Y, Jhang J, Kuo H, Huang H, et al.
Diagnostics (Basel) . 2024 Mar; 14(5). PMID: 38472940
Bladder cancer (BCa) is a significant health issue and poses a healthcare burden on patients, highlighting the importance of an effective detection method. Here, we developed a urine DNA methylation...
9.
Chua P, Ow S, Ng C, Huang W, Low J, Tan P, et al.
Cancer Cell Int . 2024 Feb; 24(1):59. PMID: 38321552
Peroxiredoxin 3 (PRDX3), a mitochondrial hydrogen peroxide scavenger, is known to be upregulated during tumorigenesis and cancer progression. In this study, we provide evidence for the first time that PRDX3...
10.
Tseng Y, Chiu Y, Pham V, Wu W, Le-Vu T, Wang C, et al.
ACS Sens . 2024 Jan; 9(1):455-463. PMID: 38234004
Selective detection of biomarkers at low concentrations in blood is crucial for the clinical diagnosis of many diseases but remains challenging. In this work, we aimed to develop an ultrasensitive...