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Michael W Collard

Explore the profile of Michael W Collard including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
McGee S, Rajamanickam S, Adhikari S, Falayi O, Wilson T, Shayota B, et al.
Hum Mol Genet . 2022 Aug; 32(3):386-401. PMID: 35981081
De novo deleterious and heritable biallelic mutations in the DNA binding domain (DBD) of the transcription factor deformed epidermal autoregulatory factor 1 (DEAF1) result in a phenotypic spectrum of disorders...
2.
Jensik P, Vargas J, Reardon S, Rajamanickam S, Huggenvik J, Collard M
PLoS One . 2014 Dec; 9(12):e115908. PMID: 25531106
DEAF1 is a transcriptional regulator associated with autoimmune and neurological disorders and is known to bind TTCG motifs. To further ascertain preferred DEAF1 DNA ligands, we screened a random oligonucleotide...
3.
Vulto-van Silfhout A, Rajamanickam S, Jensik P, Vergult S, De Rocker N, Newhall K, et al.
Am J Hum Genet . 2014 Apr; 94(5):649-61. PMID: 24726472
Recently, we identified in two individuals with intellectual disability (ID) different de novo mutations in DEAF1, which encodes a transcription factor with an important role in embryonic development. To ascertain...
4.
Jensik P, Huggenvik J, Collard M
PLoS One . 2012 Mar; 7(3):e33404. PMID: 22442688
Deformed Epidermal Autoregulatory Factor 1 (DEAF1) is a transcription factor linked to suicide, cancer, autoimmune disorders and neural tube defects. To better understand the role of DEAF1 in protein interaction...
5.
Jensik P, Huggenvik J, Collard M
J Biol Chem . 2004 May; 279(31):32692-9. PMID: 15161925
Deformed epidermal autoregulatory factor-1 (DEAF-1) is a DNA-binding protein required for embryonic development and linked to clinical depression and suicidal behavior in humans. Although primarily nuclear, cytoplasmic localization of DEAF-1...