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Michael Tschannen

Explore the profile of Michael Tschannen including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 746
Followers 0
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Recent Articles
1.
Hall W, Mathison A, DeVoe E, Tschannen M, Wendt-Andrae J, Straza M, et al.
Int J Radiat Oncol Biol Phys . 2024 May; 120(2):570-578. PMID: 38819340
Purpose: Changes in quantitative magnetic resonance imaging (qMRI) are frequently observed during chemotherapy or radiation therapy (RT). It is hypothesized that qMRI features are reflective of underlying tissue responses. It's...
2.
Hong-Le T, Crouse W, Keele G, Holl K, Seshie O, Tschannen M, et al.
Diabetes . 2022 Oct; 72(1):135-148. PMID: 36219827
Despite the successes of human genome-wide association studies, the causal genes underlying most metabolic traits remain unclear. We used outbred heterogeneous stock (HS) rats, coupled with expression data and mediation...
3.
Zimmermann M, Mathison A, Stodola T, Evans D, Abrudan J, Demos W, et al.
Front Oncol . 2021 Mar; 11:606820. PMID: 33747920
We investigated germline variation in pancreatic ductal adenocarcinoma (PDAC) predisposition genes in 535 patients, using a custom-built panel and a new complementary bioinformatic approach. Our panel assessed genes belonging to...
4.
Keele G, Prokop J, He H, Holl K, Littrell J, Deal A, et al.
Obesity (Silver Spring) . 2017 Dec; 26(1):213-222. PMID: 29193816
Objective: Obesity is a major risk factor for multiple diseases and is in part heritable, yet the majority of causative genetic variants that drive excessive adiposity remain unknown. Here, outbred...
5.
Tschannen M, Vlachopoulos L, Gerber C, Szekely G, Furnstahl P
Med Image Anal . 2016 Mar; 31:88-97. PMID: 26999616
In shoulder arthroplasty, the proximal humeral head is resected by sawing along the cartilage-bone transition and replaced by a prosthetic implant. The resection plane, called articular margin plane (AMP), defines...
6.
Tsaih S, Holl K, Jia S, Kaldunski M, Tschannen M, He H, et al.
Genetics . 2014 Sep; 198(1):17-29. PMID: 25236446
The genetic basis of type 2 diabetes remains incompletely defined despite the use of multiple genetic strategies. Multiparental populations such as heterogeneous stocks (HS) facilitate gene discovery by allowing fine...
7.
Du M, Yuan T, Schilter K, Dittmar R, Mackinnon A, Huang X, et al.
Hum Mol Genet . 2014 Aug; 24(1):154-66. PMID: 25149474
Chromosome 8q24 locus contains regulatory variants that modulate genetic risk to various cancers including prostate cancer (PC). However, the biological mechanism underlying this regulation is not well understood. Here, we...
8.
De Luca V, Tschannen M, Szekely G, Tanner C
Med Image Comput Comput Assist Interv . 2014 Feb; 16(Pt 1):518-25. PMID: 24505706
We propose a learning-based method for robust tracking in long ultrasound sequences for image guidance applications. The framework is based on a scale-adaptive block-matching and temporal realignment driven by the...
9.
Hall C, Tschannen M, Worthey E, Kristich C
Antimicrob Agents Chemother . 2013 Oct; 57(12):6179-86. PMID: 24080657
Enterococcus faecalis is a Gram-positive bacterium that is a major cause of hospital-acquired infections, in part due to its intrinsic resistance to cephalosporins. The mechanism that confers intrinsic cephalosporin resistance...
10.
Huang X, Yuan T, Tschannen M, Sun Z, Jacob H, Du M, et al.
BMC Genomics . 2013 May; 14:319. PMID: 23663360
Background: Exosomes, endosome-derived membrane microvesicles, contain specific RNA transcripts that are thought to be involved in cell-cell communication. These RNA transcripts have great potential as disease biomarkers. To characterize exosomal...