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Michael Thrippleton

Explore the profile of Michael Thrippleton including associated specialties, affiliations and a list of published articles. Areas
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Citations 38
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Recent Articles
1.
Jochems A, Munoz Maniega S, Clancy U, Arteaga-Reyes C, Garcia D, Chappell F, et al.
Neurology . 2025 Feb; 104(4):e213323. PMID: 39899790
Background And Objectives: White matter hyperintensities (WMHs) are the commonest imaging marker of cerebral small vessel disease (SVD) and a major cause of cognitive decline and vascular dementia. WMHs typically...
2.
Xu Y, Chappell F, Valdes Hernandez M, Arteaga-Reyes C, Clancy U, Garcia D, et al.
Neurology . 2024 Oct; 103(10):e209973. PMID: 39447100
Background And Objectives: A quarter of ischemic strokes are of lacunar clinical subtype and have an underlying recent small subcortical infarct (RSSI), but their long-term outcomes remain poorly characterized. Hemosiderin...
3.
Clancy U, Arteaga-Reyes C, Garcia D, Hewins W, Locherty R, Valdes Hernandez M, et al.
Neurology . 2024 Aug; 103(5):e209750. PMID: 39159417
Background And Objectives: Factors associated with cerebral small vessel disease (SVD) progression, including incident infarcts, are unclear. We aimed to determine the frequency of incident infarcts over 1 year after...
4.
Saenz de Villaverde Cortabarria A, Zhang J, Valdes Hernandez M, Clancy U, Sakka E, Ferguson K, et al.
J Neurol Sci . 2023 Jul; 451:120735. PMID: 37499621
Background: The paranasal sinus mucosal thickening, visible in magnetic resonance imaging (MRI), maybe a source of inflammation in microvessels, but its relationship with small vessel disease (SVD) is unclear. We...
5.
Marchena-Romero K, Ji X, Sommer R, Centen A, Ramirez J, Poulin J, et al.
Front Neurol . 2023 Jul; 14:1199805. PMID: 37396759
Background: Conventional cerebrovascular reactivity (CVR) estimation has demonstrated that many brain diseases and/or conditions are associated with altered CVR. Despite the clinical potential of CVR, characterization of temporal features of...
6.
Mckinnon K, Galdi P, Blesa-Cabez M, Sullivan G, Vaher K, Corrigan A, et al.
JAMA Netw Open . 2023 May; 6(5):e2316067. PMID: 37256618
Importance: Preterm birth and socioeconomic status (SES) are associated with brain structure in childhood, but the relative contributions of each during the neonatal period are unknown. Objective: To investigate associations...
7.
Rudilosso S, Stringer M, Thrippleton M, Chappell F, Blair G, Garcia D, et al.
J Cereb Blood Flow Metab . 2023 May; 43(9):1490-1502. PMID: 37132279
Blood-brain barrier (BBB) is known to be impaired in cerebral small vessel disease (SVD), and is measurable by dynamic-contrast enhancement (DCE)-MRI. In a cohort of 69 patients (42 sporadic, 27...
8.
Rudilosso S, Chui E, Stringer M, Thrippleton M, Chappell F, Blair G, et al.
Neurology . 2022 May; 99(5):e440-e452. PMID: 35606147
Background And Objectives: Magnetic resonance susceptibility-weighted imaging (SWI) can identify small brain blood vessels that contain deoxygenated blood due to its induced magnetic field disturbance. We observed focal clusters of...
9.
Zhang J, Lim H, Chappell F, Clancy U, Wiseman S, Valdes-Hernandez M, et al.
Neurobiol Aging . 2021 Jul; 106:130-138. PMID: 34274698
Raised signal in cerebrospinal fluid (CSF) on fluid-attenuated inversion recovery (FLAIR) may indicate raised CSF protein or debris and is seen in inferior frontal sulci on routine MRI. To explore...
10.
Blowers S, Marshall I, Thrippleton M, Andrews P, Harris B, Bethune I, et al.
Sci Rep . 2018 May; 8(1):7877. PMID: 29777174
Macro-modeling of cerebral blood flow can help determine the impact of thermal intervention during instances of head trauma to mitigate tissue damage. This work presents a bioheat model using a...