Michael Telias
Overview
Explore the profile of Michael Telias including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
357
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0
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Recent Articles
1.
Abraham A, Telias M
Front Cell Neurosci
. 2025 Feb;
19:1536452.
PMID: 39944766
Many retinal diseases are characterized by direct or indirect retinal ganglion cell (RGC) neurodegeneration. In glaucoma and optic nerve neuropathies, RGCs are the primary affected cells, whereas in photoreceptor dystrophies,...
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Telias M, Sit K, Frozenfar D, Smith B, Misra A, Goard M, et al.
Sci Adv
. 2022 Mar;
8(11):eabm4643.
PMID: 35302843
Rod and cone photoreceptors degenerate in retinitis pigmentosa (RP). While downstream neurons survive, they undergo physiological changes, including accelerated spontaneous firing in retinal ganglion cells (RGCs). Retinoic acid (RA) is...
5.
Telias M, Ben-Yosef D
Front Mol Neurosci
. 2021 Aug;
14:680018.
PMID: 34421534
The canonical Wnt/β-catenin pathway is a master-regulator of cell fate during embryonic and adult neurogenesis and is therefore a major pharmacological target in basic and clinical research. Chemical manipulation of...
6.
Telias M, Nawy S, Kramer R
Front Neurosci
. 2021 Jan;
14:618019.
PMID: 33390897
Vision impairment and blindness in humans are most frequently caused by the degeneration and loss of photoreceptor cells in the outer retina, as is the case for age-related macular degeneration,...
7.
Denlinger B, Helft Z, Telias M, Lorach H, Palanker D, Kramer R
JCI Insight
. 2019 Dec;
5(2).
PMID: 31846440
Vision loss in age-related macular degeneration (AMD) stems from disruption of photoreceptor cells in the macula, the central retinal area required for high-acuity vision. Mice and rats have no macula,...
8.
Telias M
Curr Pharm Des
. 2019 Nov;
25(41):4394-4404.
PMID: 31682210
Background: Fragile X syndrome (FXS) is the most common form of monogenic hereditary cognitive impairment, including intellectual disability, autism, hyperactivity, and epilepsy. Methods: This article reviews the literature pertaining to...
9.
Telias M
Methods Mol Biol
. 2019 Mar;
1942:155-162.
PMID: 30900183
Despite almost 30 years of biomedical research, a treatment or cure for fragile X syndrome (FXS) is not yet available. The reasons behind this are varied, and among them are...
10.
Telias M, Segal M
Methods Mol Biol
. 2019 Mar;
1942:131-139.
PMID: 30900181
Performing electrophysiological recordings from human neurons that have been differentiated in vitro, as compared to primary cultures, raises many challenges. However, patch-clamp recording from neurons derived from stem cells provides...